7d内短暂性脑缺血发作进展至脑梗死相关因素分析  

Risk Factors for Transient Ischemic Attack Progressing to Cerebral Infarction within 7 Days

作　　者：吴跃华[1] 路雅宁[1] 肖雅娟[1] 林黎明[1] 徐秀芝[1] Wu Yuehua;Lu Yaning;Xiao Yajuan;Lin Liming;Xu Xiuzhi(Department of Neurology, the Fourth Hospital of Baotou, Baotou 014030, China)

机构地区：[1]内蒙古自治区包头市第四医院神经内科

出　　处：《国际老年医学杂志》2019年第3期140-142,共3页International Journal of Geriatrics

基　　金：包头市卫生基金(wsjj2016019)

摘　　要：目的 探讨7d内短暂性脑缺血发作(TIA)进展至脑梗死的相关危险因素.方法 选取我科100例短暂性脑缺血发作病例,按7d内是否发生脑梗死,将其分为进展组及非进展组.对两组患者的年龄、性别、吸烟史、饮酒史、脑卒中家族史、既往脑梗死病史、糖尿病史、高血压病史、高脂血症、心脏病、高同型半胱氨酸血症、发作次数>3次、颈动脉斑块等进行比较,采用ABCD2评分法评估短暂性脑缺血发作患者7d内进展为脑梗死的情况.结果 进展组患者中有糖尿病、高血压病史者、颈动脉斑块者、发作次数>3次者较非进展组多见(P<0.05);ABCD2评分值的高危组TIA患者脑梗死发生率明显高于中危组和低危组(P<0.01).结论 高血压病、糖尿病、颈动脉斑块、发作次数>3次、ABCD2评分≥6分与短暂性脑缺血发作进展至脑梗死相关.Objective To explore the risk factors for transient ischemic attack ( TIA ) progressing to cerebral infarction within 7 days. Methods A total of 100 patients with TIA in our hospital were enrolled. According to the occurrence of cerebral infarct within 7 days, the patients were divided into CIP group (TIA progressing to cerebral infarct) and non-CIP group ( TIA no progressing to cerebral infarct). The age, gender, the history of tobacco and alcohol, family history of cerebral stroke, history of cerebral infarction, diabetes, hypertension, hyperlipidemia, heart disease, hyperhomocysteinemia, frequent attacks >3 times and carotid atherosclerotic plaques were analyzed. ABCD2 score was used to evaluate the risk of TIA progressing to cerebral infarction within 7 days. According to the ABCD2 score, the patients were divided into high, moderate and low risk group. Results There were more cases with hypertension, diabetes, carotid atherosclerotic plaques and frequent attacks>3 times in CIP group than in non-CIP group (P< 0.05 ). The incidence of cerebral infarct in the high risk group was higher than that in the moderate risk group and low risk group (P<0.01 ). Conclusion Hypertension, diabetes, carotid atherosclerotic plaques, frequent attacks>3 times and the ABCD2 scale ≥6 are risk factors for TIA progressing to cerebral infarct.

关 键 词：短暂性脑缺血发作 脑梗死 ABCD2评分 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]