卒中后抑郁的发生情况与危险因素研究  

Incidence and risk factors of poststroke depression

作　　者：陈星宇 蔡伟彬 余恒旺 CHEN Xing-yu;CAI Wei-bin;YU Heng-wang(Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Department of Acupuncture Rehabilitation,Guangdong Second Traditional Chinese Medicine Hospital,Guangzhou 510095,China;Department of Neurology,Maoming Traditional Chinese Medicine Hospital,Guangdong,Maoming 525000,China)

机构地区：[1]广州中医药大学,广州510405 [2]广东省第二中医院针灸康复科,广州510095 [3]广州中医药大学附属茂名中医院神经内科,广东茂名525000

出　　处：《中国医学前沿杂志（电子版）》2019年第6期125-128,共4页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：目的调查卒中后抑郁(post-stroke depression,PSD)的发生情况,分析影响PSD发生的危险因素。方法采用随机抽样法于广州中医药大学附属茂名中医院收集100例符合纳入标准的脑卒中患者的病历资料,依据汉密尔顿抑郁量表(Hamilton depression scale,HAMD)(17项)评分将入选患者分为PSD组和非PSD组,计算PSD发生率。采用单因素和多因素分析探讨导致PSD的危险因素。结果100例卒中患者中有64例发生PSD,发生率为64%。年龄>60岁,文化程度低,合并多种慢性病,卒中位于额叶、丘脑、基底节、脑干以及左侧大脑半球或大脑前部均为发生PSD的危险因素(均P<0.05)。结论年龄>60岁,文化程度低,合并慢性病种类多,卒中位于额叶、丘脑、基底节、脑干以及左侧大脑半球或大脑前部均是导致PSD的危险因素,针对上述危险因素应及时干预,以降低PSD发生率。Objective To investigate the incidence of post-stroke depression (PSD) and analyze the risk factors of PSD.Method The random sampling method was used to collect the data of 100 cases of stroke patients who met the inclusion criteria in Maoming Traditional Chinese Medicine Hospital,and demographic data were collected,the selected patients were divided into PSD group and non-PSD group according to the score of Hamilton depression scale (HAMD)(17 items),the incidence of PSD was calculated. Using univariate and multivariate analysis to explore the risk factors of PSD.Result PSD occurred in 64 of 100 stroke patients, with an incidence of 64%.Age > 60 years old,low education level,complicated with a variety of chronic diseases,stroke sites in the frontal lobe,thalamus,basal ganglia,brain stem,left cerebral hemisphere or anterior part of the brain were the risk factors of PSD (all P < 0.05).Conclusion Age > 60 years old,low education level,complicated with a variety of chronic diseases,stroke sites in the frontal lobe,thalamus,basal ganglia,brain stem,left cerebral hemisphere or anterior part of the brain are the risk factors of PSD,we should take intervention according to the above risk factors in order to reduce the incidence of PSD.

关 键 词：卒中后抑郁 发生率 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]