重症急性胰腺炎治疗的新理念  

New idea of severe acute pancreatitis therapeutics

作　　者：巫协宁[1] 汪佩文[1] 万荣[1] 宛新建[2] WU Xiening;WANG Peiwen;WAN Rong;WAN Xinjian(Department of Gastroenterology,Shanghai General Hospital,Shanghai Jiao Tong University,Shanghai 200080,China;Digestive Endoscopy Section,Shanghai General Hospital,Shanghai Jiao Tong University,Shanghai 200080,China)

机构地区：[1]上海交通大学附属第一人民医院消化科,上海200080 [2]上海交通大学附属第一人民医院消化内镜中心,上海200080

出　　处：《胃肠病学和肝病学杂志》2019年第6期601-605,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：重症急性胰腺炎(severe acute pancreatitis,SAP)是多因素诱发、多环节累及并有多种严重并发症和高病死率的疾病,治疗采用奥曲肽、血浆、白蛋白和柴芍承气汤的三联疗法,继以营养支持,对其多个重要环节采取多种预防性措施多管齐下的治疗策略和方法,阻断其级联反应、防止疾病的发展和并发症的发生。前阶段(1995-2002年)40例均为特发性SAP,无死亡也无严重并发症,后阶段(2008-2018年)63例包括胆源性与高脂血症性SAP,病情更严重,共103例,死亡3例,死亡率2.9%,有多种严重并发症也被成功救治。文中特别提到预防性治疗这一理念和实践经验的重要性,也有不少自主创新的内容值得提供给国内同道们参考。Severe acute pancreatitis(SAP) is a disease induced by multiple factors and involving multiple links with high mortality and severe complication rates. Treatment strategy is by adopting multiple preventive measures directing against its several essential links at the same moment, to interrupt its cascade response, prevent development of severe complications and disease progression. In the former period(1995-2002), 40 cases were all idiopathic SAP with no mortality and no severe complications;in the latter period(2008-2018), 63 cases including some hyperlipidemic and biliary origin SAP, these were even more severe, altogether 103 cases with 3 deseased and a mortality rate of 2.9%, many cases with severe complications had all been cured. Within this article, there are many self-devised innovations, in particular, the new idea of preventive treatment and break through approach can be provided to our domestic colleagues for their reference.

关 键 词：重症急性胰腺炎 治疗策略和疗法 新理念 预防性治疗 

分 类 号：R576[医药卫生—消化系统]