DynaCT对肝转移瘤介入治疗具有指导意义  

DynaCT has Guiding Significance for Interventional Treatment of Hepatic Metastases

作　　者：朱丽娜 谢宝杰 殷风华 李智岗 Zhu Lina;Xie Baojie;Yin Fenghua;Li Zhigang(The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011)

机构地区：[1]河北医科大学第四医院

出　　处：《基因组学与应用生物学》2019年第5期2265-2269,共5页Genomics and Applied Biology

摘　　要：为了探讨锥形束CT (DynaCT)在肝癌患者实施经导管肝动脉化疗栓塞(TACE)手术治疗中的指导作用、栓塞效果评估中的价值,本研究选取了2012年3月至2015年5月在本院实施TACE手术治疗的102例原发性肝癌或转移性肝癌患者进行研究。通过对102例患者病灶进行手术前螺旋CT检测、术中数字减影血管造影(DSA)及DynaCT检测,并对比DSA与DynaCT对肝癌病灶、供血动脉、术后栓塞效果的检测结果。本研究发现术前普通螺旋CT共计检出病灶105个,术中DSA检出病灶数目176个,DynaCT术中检出肿瘤病灶285个;DynaCT和DSA的平均检出病灶数目均显著的高于普通螺旋CT (p<0.05),DynaCT平均检出病灶数目均显著的高于DSA (p<0.05);DynaCT的病灶供血动脉检出率为86.67%,显著地高于DSA (55.68%)(p<0.05);DynaCT检出的285个病灶对栓塞效果评估结果与实际栓塞效果一致的有271个病灶(95.09%),DSA评估结果与实际结果一致的有138个病灶(78.41%),DynaCT对于TACE术后效果评估的一致性高于DSA (p<0.05)。本研究表明,DynaCT在肝癌患者实施TACE手术治疗中能够更有效的发现病灶,指导栓塞操作。To investigate the guiding role of cone beam CT(DynaCT) in transcatheter arterial chemoembolization(TACE) for patients with hepatocellular carcinoma(HCC) and to evaluate the effect of transcatheter arterial chemoembolization(TACE), we selected and studied 102 cases of primary liver cancer or metastatic liver cancer which were treated with surgical treatment of TACE in our hospital from March 2012 to May 2015. By conducting the spiral CT detection of lesions in 102 patients before operation, digital subtraction angiography and DynaCT detecting in operation, and comparing the detection results of DSA and DynaCT on the effect of embolization,detection of HCC lesions artery, postoperative, we found that 105 lesions were detected in preoperative spiral CT totally, and the number of lesions detected by DSA was 176, by DynaCT was 285 in operative;The average number of lesions detected by DynaCT and DSA were significantly higher than that of spiral CT(p<0.05), the average number of lesions detected by DynaCT were significantly higher than that of DSA(p<0.05);The artery lesions detection rate of DynaCT was 86.67%, which was significantly higher than that of DSA(55.68%)(p<0.05);There was 271 lesions of whose evaluation results of embolization effect were consistent with the actual effect of embolization(95.09%) in 285 lesions detected by DynaCT. And 138 lesions whose DSA evaluation results were consistent with the actual effect(78.41%), the consistency of effect evaluation by DynaCT after TACE was higher than DSA(p<0.05). Our research indicted that DynaCT can find the lesion more effectively and guide the operation of embolization in TACE operation for liver cancer patients.

关 键 词：锥形束CT 肝癌 经导管肝动脉化疗栓塞术 数字减影血管造影 

分 类 号：R735.7[医药卫生—肿瘤]