外膜滋养血管在动脉粥样硬化易损斑块中的研究现状  

Research advance of outer membrane vasa vasorum in atherosclerotic vulnerable plaque

作　　者：漆仲文 李萌[2] 朱科 张军平[2] QI Zhongwen;LI Meng;ZHU Ke;ZHANG Junping(Graduate School,Tianjin University of TCM,Tianjin 300193,China;The First Affiliated Hospital of Tianjin University of TCM,Tianjin 300193,China;Zhengzhou Chinese Medicine Hospital,Zhengzhou,Henan 450000,China)

机构地区：[1]天津中医药大学,天津市300193 [2]天津中医药大学第一附属医院,天津市300193 [3]郑州市中医院,河南省郑州市450000

出　　处：《中国动脉硬化杂志》2019年第6期542-546,共5页Chinese Journal of Arteriosclerosis

基　　金：国家自然科学基金项目(81804046);国家“万人计划”百千万工程领军人才项目(20160621);天津市高校“学科领军人才培养计划”项目

摘　　要：随着对动脉粥样硬化(As)的深入研究,促进易损斑块的稳定性成为As新的治疗理念。在As“由内而外”学说中血管内膜的病理改变成为始动因素,然而近年研究表明外膜新生滋养血管(VV)在As“由外向内”发病机制中起到关键作用,总之,对于As的治疗已从保护血管内膜转变为调节外膜VV。With the in-depth study of atherosclerosis (As),promoting the stability of vulnerable plaque has become a new therapeutic concept for As.In the “inside-out” theory of As,the pathological changes of the intima are the initiating factors.However,recent studies have shown that the vasa vasorum (VV) plays a key role in the pathogenesis of As from the outside to the inside.In summary,treatment of As has changed from protecting the intima to regulating the outer membrane VV.

关 键 词：滋养血管 易损斑块 动脉粥样硬化 

分 类 号：R363[医药卫生—病理学] R5[医药卫生—基础医学]