全胸腔镜手术治疗高龄全胸腔镜手术治疗高龄Ⅰa～Ⅲa期肺癌患者的疗效及生存分析  

Clinical efficacy and survival analysis of complete thoracoscopic surgery for elderly stage Ⅰa-Ⅲa lung cancer patients

作　　者：邓雪丽 戴小峰 黄柒彬[2] 邹恭道[2] DENG Xueli;DAI Xiaofeng;HUANG Qibin;ZOU Gongdao(Operating Room, Jingzhou Hospital of Traditional Chinese Medicine, Jingzhou 434000, Hubei, China;Department of Thoracic Surgery, the First People’s Hospital in Jingzhou City of Hubei Province, Jingzhou 434000, Hubei, Chin)

机构地区：[1]荆州市中医医院手术室,湖北荆州434000 [2]荆州市第一人民医院胸外科,湖北荆州4340000

出　　处：《癌症进展》2019年第12期1415-1418,共4页Oncology Progress

摘　　要：目的探讨全胸腔镜手术治疗高龄Ⅰa~Ⅲa期肺癌患者的疗效及生存情况。方法根据手术方法的不同将行手术切除的96例高龄(年龄﹥75岁且﹤85岁)Ⅰa~Ⅲa期原发性肺癌患者分为观察组(n=48)和对照组(n=48)。观察组患者行全胸腔镜下肺叶切除术,对照组患者行开胸肺叶切除术,比较两组患者的手术相关指标、术后并发症发生情况及1年生存情况。结果观察组患者的手术时间、术后下床活动时间均明显短于对照组,术中出血量、术后引流量均明显低于对照组,差异均有统计学意义(P﹤0.01);观察组和对照组患者的手术根治率、淋巴结清扫数目、拔管时间比较,差异均无统计学意义(P﹥0.05);观察组患者的术后并发症总发生率明显低于对照组(P﹤0.01);两组患者的1年生存率比较,差异无统计学意义(P﹥0.05)。结论全胸腔镜手术治疗高龄Ⅰa~Ⅲa期肺癌患者的疗效与传统开胸手术相当,且不良反应发生少,对患者的影响较小,更有利于患者的术后恢复。Objective To investigate the clinical efficacy of complete thoracoscopic surgery for elderly patients with stage Ia-IIIa lung cancer and their survival situation. Method A total of 96 elderly patients (>75 years and <85 years) with primary lung cancer staging Ia to IIIa were selected and divided into observation group (n=48) and control group (n= 48) according to the operative methods they accepted. The observation group underwent complete thoracoscopic lobectomy and the control group underwent conventional thoracotomy lobectomy. The surgery related indicators, incidence of complications and 1-year survival were compared between the two groups. Result The operation time and the postoperative out-of-bed ambulation time in observation group were shorter than those in control group, and the volume of intraoperative blood loss and postoperative suction drainage were less than those in control group, the differences were statistically significant (P<0.01). The radical operation success rate, number of lymph node dissection and extubation time between the two groups showed no significant difference (P>0.05). The postoperative complications rate in observation group was significant lower than that in control group (P<0.01). There was no significant difference in 1-year survival between the two groups (P>0.05). Conclusion The clinical efficacy of complete thoracoscopic lobectomy in the treatment of elderly patients with stage Ia-IIIa lung cancer is comparable to that of traditional thoracotomy. Thoracoscopic lobectomy is conducive to postoperative recovery of patient with less adverse events and less influence.

关 键 词：全胸腔镜手术 高龄 Ⅰa~Ⅲa期肺癌 临床疗效 

分 类 号：R734.2[医药卫生—肿瘤]