腹腔热灌注化疗在胃肠道恶性肿瘤腹膜转移中的应用  

Application of hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis metastasis of gastrointestinal tumor

作　　者：杨肖军[1] 熊斌[1] YANG Xiaojun;XIONG Bin(Department of Gastrointestinal Surgery, ZhongnanHospital of Wuhan University,Hubei Province, Wuhan 430071, China)

机构地区：[1]武汉大学中南医院胃肠外科,430071

出　　处：《临床外科杂志》2019年第5期443-446,共4页Journal of Clinical Surgery

摘　　要：腹膜癌(peritoneal carcinomatosis,PC)是腹膜表面播散性生长的一类局部区域性肿瘤,常见于胃肠道恶性肿瘤腹膜转移,它被认为是一种终末期疾病,既往常采用姑息性治疗。细胞减灭术(cytoreductive surgery,CRS)加术中、术后早期腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC),联合围手术期系统化疗的综合治疗策略是目前治疗PC的标准方案,可降低腹膜肿瘤复发率、延长患者生存时间,并取得了一定的临床疗效。本文就腹腔热灌注化疗在胃肠道恶性肿瘤腹膜转移中的应用进行概述。Peritoneal carcinomatosis(PC)is a type of localized tumor that spreads on the peritoneal surface is mostly a peritoneal metastasis of gastrointestinal tumors.PC is considered to be an end-stage disease,and palliative treatment is often used.The combination of cytoreductive surgery(CRS),intraoperative or postoperative early hyperthermic intraperitoneal chemotherapy(HIPEC)and perioperative systemic chemotherapy is the current standard treatment for PC.The clinical effect of CRS and HIPEC can reduce the recurrence rate of peritoneal tumors and prolong the survival of patients.This article summarizes the application of peritoneal hyperthermic perfusion chemotherapy in peritoneal metastasis of gastrointestinal tumors.

关 键 词：腹腔热灌注化疗 胃肠道恶性肿瘤 腹膜转移 

分 类 号：R735[医药卫生—肿瘤]