侵袭性垂体腺瘤相关代谢标志物与MR评估的研究进展  

Recent advances in metabolic markers related to invasive pituitary adenomas and magnetic resonance evaluation

作　　者：吴箭午 张建鹤 王守森 Wu Jianwu;Zhang Jianhe;Wang Shousen(Department of Neurosurgery,Dongfang Hospital,Xiamen University (900^th Hospital of Joint Logistics Team),Fuzhou 350025,China)

机构地区：[1]厦门大学附属东方医院(联勤保障部队第九〇〇医院)神经外科,福州350025

出　　处：《中华神经医学杂志》2019年第6期639-643,共5页Chinese Journal of Neuromedicine

基　　金：福建省科技计划引导性项目(2018Y0067);南京军区福州总医院创新团队基金(2014CXTD071);南京军区福州总医院青年育才项目(2014Q32).

摘　　要：垂体腺瘤是颅内常见良性肿瘤,但部分具有侵袭性.近年来对侵袭性垂体腺瘤的研究主要集中在基因组学、蛋白组学及影像学方面,而在其代谢物质与MR征象相关性方面的研究虽然不多,却有助于了解肿瘤细胞代谢和对相关影像特征的阐释.本文现就侵袭性垂体腺瘤的MR评估及代谢标志物研究进展综述如下.Pituitary adenomas are common benign intracranial tumors;however, some pituitary adenomas are invasive. Recent studies on the invasive pituitary adenomas have mainly focused on genomics, proteomics, and imaging. Although there are few studies on metabolites and magnetic resonance (MR) signs of pituitary adenomas, these studies can aid in understanding the metabolism of tumor cells and relevant imaging characteristics. This paper reviews the research progress on MR imaging evaluation and metabolites in invasive pituitary adenomas.

关 键 词：侵袭性垂体腺瘤 细胞代谢 核磁共振 

分 类 号：R736.4[医药卫生—肿瘤]