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作 者:郭晓娜[1] 叶秀玲[1] 张金嵩[2] 杨倩倩[3] 刘德成[3] Guo Xiaona;Ye Xiuling;Zhang Jinsong;Yang Qianqian;Liu Decheng(Department of Ophthalmology,Beijing Aerospace center Hospital,Beijing 100015,China;Department of Ophthalmology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Ophthalmology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
机构地区:[1]航天中心医院眼科,北京100015 [2]郑州大学第一附属医院眼科,郑州450052 [3]郑州市第七人民医院眼科,450016
出 处:《中华眼外伤职业眼病杂志》2019年第5期385-389,共5页Chinese Journal of Ocular Trauma and Occupational Eye Disease
摘 要:目的评价后部眼球筋膜下注射曲安奈德治疗非动脉炎性前部缺血性视神经病变的效果。方法回顾性分析2015年6月至2017年5月非动脉炎性前部缺血性视神经病变60例(60眼)的临床资料。患者随机分为两组。治疗组30例接受复方樟柳碱颞浅动脉旁注射联合曲安奈德20mg后部眼球筋膜下注射;对照组30例单纯应用复方樟柳碱颞浅动脉旁注射治疗。结果治疗后60d两组最佳矫正视力比较,治疗组视力提高优于对照组,差异有统计学意义(χ^2=17.800,P=0.003)。治疗组有视野检查15眼中治疗后好转14眼(93.33%);对照组有视野检查15眼中治疗后好转3眼(16.67%),两组间差异有统计学意义(χ^2=18.680,P=0.0025)。结论复方樟柳碱联合曲安奈德治疗非动脉炎前部缺血性视神经病变优于单纯复方樟柳碱的治疗。Objective To evaluate the efficacy of subtenon injection of triamcinolone acetonide(TA) for non-arteritic anterior ischemic optic neuropathy (NAION). Methods The data of 60 eyes of 60 patients with NAION from Jun. 2015 to May 2017 were analyzed retrospectively. All cases were randomly divided into two groups, 30 eyes of 30 patients in each group. The treatment group underwent injection of compound anisodine around superficial temporal artery combined with subtenon injection of TA(20 mg). The control group underwent injection of compound anisodine around superficial temporal artery. Results The best corrected visual acuity (BCVA), visual field and optic papilla swelling were improved 60 days after treatment. BCVA of treatment group after treatment was better than that of the control group(χ^2=17.800, P=0.003). In the treatment group, the visual field was improved in 14 eyes (93.33%) after treatment in 15 eyes with visual field examination.In the control group, the visual field was improved in 3 eyes (16.67%) after treatment in 15 eyes with visual field examination. The difference was significant between the two groups(χ^2=18.680, P=0.0025). Conclusion Compound anisodine combined with TA is more effective than compound anisodine separately on the treatment of NAION.
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