结直肠癌筛查的临床研究进展  

Research progress in colorectal cancer screening

作　　者：郝敬鹏[1] 王晖 史刚刚[1] 韩梅 李鹏昊[1] 李梦龙 Hao Jingpeng;Wang Hui;Shi Ganggang;Han Mei;Li Penghao;Li Menglong(Department of Anorectal Surgery,the Second Hospital of Tianjin Medical University,Tianjin 300211,China)

机构地区：[1]天津医科大学第二医院肛肠外科,300211

出　　处：《国际生物医学工程杂志》2019年第2期177-180,共4页International Journal of Biomedical Engineering

摘　　要：结直肠癌(CRC)发病率高,对人类健康威胁大。60%~70%的CRC来源于结直肠息肉,而息肉可经内镜下电切等方法治疗,杜绝其癌变的可能。因此,在CRC的防治中,筛查的作用和意义重大。CRC的筛查手段包括最常用的粪便隐血试验(FOBT)和更敏感的粪便免疫化学检测(FIT),性价比较高的纤维乙状结肠镜和结肠镜,作为有益补充的CT结肠镜(CTC),以及尚待完善的粪便DNA检查和CRC血液学筛查等。对CRC筛查技术进行综述,介绍其原理、特点以及最新的研究进展,为CRC筛查技术的应用与发展提供一定理论依据。The incidence of colorectal cancer is high threatening human health. About 60%~70% cases of CRC are derived from colorectal polyps,which can be treated by endoscopic electrotomy to prevent the possibility of canceration. Therefore,in the prevention and treatment of CRC,the role of screening is of great significance. CRC screening methods include the most commonly used fecal occult blood test (FOBT) and the more sensitive fecal immunochemical test (FIT),cost-effective fiber sigmoidoscopy and colonoscopy,CT colonoscopy (CTC),and fecal DNA testing and immature CRC hematology screening. In this paper,the CRC screening technologies were reviewed, including the principles,characteristics and the latest research progress to provide a theoretical basis for the application and development of CRC screening technology.

关 键 词：结直肠癌 筛查技术 结肠镜 

分 类 号：R735.34[医药卫生—肿瘤]