35例老年首次非诱发性癫痫复发的临床特点及危险因素分析  

Clinical characteristics and risk factors of recurrence after unprovoked first seizure in 35 gerontal patients

作　　者：秦锡祥[1] 肖远流 陈宗梅[1] 曹柱[1] 吴锡芬[1] QIN Xi-xiang;XIAO Yuan-liu;CHEN Zong-mei;CAO Zhu;WU Xi-fen(Department of Neurology,Lianjiang People’sHospital,Lianjiang 524400,China)

机构地区：[1]广东省廉江市人民医院神经内科

出　　处：《广东医科大学学报》2019年第3期297-299,共3页Journal of Guangdong Medical University

基　　金：湛江市科技计划项目(No.2017B01113)

摘　　要：目的探讨老年首次非诱发性癫痫(UFS)复发的临床特点及危险因素。方法收集35例老年UFS复发的临床资料,总结临床特点,多因素Logistic回归分析危险因素。结果35例老年UFS复发中,全面性发作和部分性发作分别为9、26例。多因素Logistic回归分析显示病灶累及皮质、梗死灶最大截面积直径≥3cm、睡眠中发作、伴有代谢性疾病与UFS复发关系密切(P<0.05)。结论老年UFS复发以部分性发作常见;病灶累及皮质、梗死灶直径≥3cm、睡眠中发作、伴有代谢性疾病均是老年UFS复发的独立危险因素。Objective To investigate the clinical characteristics and risk factors of recurrence after unprovoked first seizure (UFS) in gerontal patients. Methods Clinical data of 35 gerontal patient with UFS recurrence were collected. Clinical characteristics and risk factors were summarized and analyzed by multiple logistic regression. Results Of 35 cases, generalized and partial seizure occurred in 9 and 26 cases, respectively. Multiple logistic regression showed that cortex involvement, maximum sectional diameter of infarction focus ≥3 cm, sleep seizure, and complicated metabolic diseases were correlated with UFS recurrence (P<0.05). Conclusion Partial seizure is common, and independent risk factors include cortex involvement, maximum sectional diameter of infarction focus ≥3 cm, sleep seizure, and complicated metabolic diseases in gerontal patients with UFS recurrence.

关 键 词：首次非诱发性癫痫 老年人 危险因素 

分 类 号：R743[医药卫生—神经病学与精神病学]