肺类癌的18 F-FDG PET-CT显像结果分析  

Evaluation of clinical value of PET-CT in pulmonary carcinoid

作　　者：张少伟[1] 李灿[2] 王观筠 温佳新[1] 任志鹏[1] 薛志强[1] Zhang Shaowei;Li Can;Wang Guanjun;Wen Jiaxin;Ren Zhipeng;Xue Zhiqiang(Department of Toracic Surgery, PLA General Hospital, Beijing 100853, China;Department of Nuclear Medicine, PLA General Hospital, Beijing 100853, China)

机构地区：[1]中国人民解放军总医院胸外科一病区,北京100853 [2]中国人民解放军总医院核医学科,北京100853

出　　处：《中华胸心血管外科杂志》2019年第6期339-342,共4页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的 回顾我院肺类癌患者的临床资料,探讨PET-CT在肺类癌上的表现及应用价值.方法 回顾性分析2008年11月至2017年3月于解放军总医院就诊的肺类癌患者的临床资料及PET-CT信息,比较肿瘤大小、病理亚型与SUVmax值的关系,评估其判断淋巴结转移的效能.结果 33例患者中,典型类癌(TC)10例,不典型类癌(AC)23例.肿瘤长径与SUVmax值正相关(P<0.001),不典型类癌的SUVmax均值较典型类癌高(11.27对3.54),控制肿瘤长径,单因素协方差分析提示病理亚型与SUVmax值相关(P=0.012);PET-CT判断肺类癌淋巴结转移的敏感度为66.7%(95%CI:12.5%~98.2%),特异度为90.9%(95%CI:83.0%~95.5%).结论 不典型类癌较典型类癌表现出更高的SUVmax,但肺类癌的PET-CT表现并无特异性,在判断淋巴结转移上有较高的特异度.Objective To assess the performance of PET-CT in pulmonary carcinoid and to evaluate the efficacy of lymph node metastasis.Methods We retrospectively collected the data of 33 patients with primary pulmonary carcinoid in our center between November 2008 and March 2017.The results of PET-CT were analysed and the relationship among pathological sub-type, tumor size and SUVmax was compared.Results Thirty-three patients had a diagnosis of carcinoid tumor, typical in 10 patients and atypical in 23 patients.The major axis of the tumor was positively correlated with the SUVmax value (P<0.001), and the mean SUVmax of the atypical carcinoid was higher than that of the typical carcinoid(11.27 vs 3.54).The major axis of the tumor was controlled.One-way covariance analysis suggested that the pathological subtype was related to SUVmax(P=0.012).Overall, PET-CT had a sensitivity of 66.7%(95%CI: 12.5%-98.2%) and specificity of 90.9%(95%CI:83. 0%-95.5%).Conclusion Atypical carcinoids showed higher SUVmax than typical carcinoids, but the PET-CT perform-ance of lung carcinoids is not specific.There was a high specificity in evaluating lymph node metastasis.

关 键 词：肺肿瘤 类癌 PET-CT 神经内分泌肿瘤 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]