综合康复干预对脑卒中合并阿尔兹海默病患者认知能力和运动能力的影响  

Effect of comprehensive rehabilitation intervention on the cognitive ability and exercise capacity in stroke patients with AD

作　　者：于洋[1] 于观潇 徐文龙[1] Yu Yang;Yu Guanxiao;Xu Wenlong(Sports Medicine and Rehabilitation Center,Qingdao Municipal Hospital,Qingdao 266071,China)

机构地区：[1]青岛市市立医院运动医学康复中心

出　　处：《中华保健医学杂志》2019年第3期234-238,共5页Chinese Journal of Health Care and Medicine

摘　　要：目的探讨综合康复干预对脑卒中合并阿尔兹海默病(AD)患者认知能力和运动能力的影响。方法选取2015年1月~2017年11月于青岛市市立医院就诊的62例已确诊为卒中合并AD的患者,随机分为观察组和对照组,各31例。对照组患者予以常规治疗和常规自我康复锻炼,观察组在对照组基础上予以多学科综合康复训练干预。观察比较两组患者干预前后认知功能、脑电特征、肌力水平、偏瘫功能和日常生活活动能力。结果治疗后观察组患者的简易精神状态检查量表(MMSE)评分、韦氏记忆测试(WMS)评分均较治疗前升高,对照组患者的MMSE评分、WMS评分均较治疗前下降,观察组患者MMSE评分、WMS评分的改变均较对照组高,差异具有统计学意义(P<0.05)。治疗后观察组患者的β1、β2均较治疗前升高,观察组的β1、β2增加值显著高于对照组,差异具有统计学意义(P<0.05);对照组患者的β1、β2与治疗前比较,差异无统计学意义(P>0.05)。治疗后,观察组患者的肌力明显好于对照组(P<0.05),观察组患者的FMA评分(35.94±5.41vs.21.15±3.16;22.92±5.97vs.15.18±2.80)、日常生活能力评定(Barthel指数)(69.47±15.25vs.51.13±12.31)均高于对照组,观察组FMA评分、Barthel指数增加值显著高于对照组,差异均具有统计学意义(P<0.05)。结论对脑卒中合并AD患者予以早期综合康复干预,可明显改善患者的认知能力与运动能力,提高患者的生活质量,值得临床推广和应用。Objective To investigate the effects of comprehensive rehabilitation intervention on the cognitive ability and exercise capacity in stroke patients with Alzheimer Disease(AD). Methods 62 patients who had been diagnosed with stroke and AD in our hospital from January 2015 to November 2017 were randomly divided into the observation and the control groups,with 31 cases in each group. Patients in the control group received routine treatment and unsupervised self-rehabilitation exercise. The observation group received multidisciplinary comprehensive rehabilitation intervention after the vital signs were stable and the symptoms were controlled. The cognitive function,EEG characteristics,muscle strength,hemiplegia function and activities of daily living were compared before and after intervention between the two groups. Results After treatment,the scores of MMSE and WMS in the observation group were higher than those before treatment,and the scores of MMSE and WMS in the control group were lower than before treatment,the changes of the scores of MMSE and WMS in the observation group were higher than those in the control group, and the difference was statistically significant(P < 0.05). After treatment,the levels of β1 and β2 in the observation group were higher than those before treatment,the added value of the levels of β1 and β2 in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P < 0.05). However,there was no significant difference between β1 and β2 in the control group compared with before treatment(P > 0.05). After treatment,the muscle strength in the observation group was significantly better than that in the control group(P < 0.05). After treatment,the score of FMA(35.94 ± 5.41 vs. 21.15 ± 3.16;22.92 ± 5.97 vs. 15.18 ± 2.80) and Barthel index(69.47 ± 15.25 vs. 51.13 ± 12.31) in the observation group were higher than those in the control group,the increased value of the score of FMA and Barthel index in the observation group

关 键 词：阿尔兹海默病 综合康复 脑卒中 认知功能 脑电特征 

分 类 号：R743.3[医药卫生—神经病学与精神病学]