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作 者:冯德航 FENG De-hang(Department of Otolaryngology, Dehong People's Hospital, Dehong, Yunnan Province, 678400 China)
机构地区:[1]德宏州人民医院耳鼻喉科
出 处:《系统医学》2019年第10期30-32,共3页Systems Medicine
摘 要:目的观察鼻侧切开术结合鼻内镜辅助治疗上颌窦癌患者的临床效果。方法随机选取该院2015年10月—2017年10月收治的48例上颌窦癌患者作为样本,将患者随机分为2组,对照组单独通过化疗或放疗方法治疗,观察组患者行鼻侧切开术结合鼻内镜辅助治疗,术后根据情况放疗或化疗。结果观察组CR率41.67%(χ^2=0.584,P=0.059)、PR率37.50%(χ^2=1.261,P=0.068)、SD率20.83%(χ^2=0.174,P=0.061)、PD率为0.00%(χ^2=0.000,P=1.000)、不良反应发生率50.00%(χ^2=0.855,P=0.095),与对照组无显著差异。结论采用鼻侧切开术结合鼻内镜辅助治疗上颌窦癌,能够有效改善患者的远期疗效,预防局部复发及淋巴结转移,延长患者寿命。Objective To observe the clinical effect of nasal resection combined with nasal endoscopy for maxillary sinus carcinoma. Methods Forty-eight patients with maxillary sinus cancer admitted in our hospital from October 2015 to October 2017 were randomly divided into two groups: the control group was treated with chemotherapy or radiotherapy alone, and the observation group was treated with nasal incision combined with nasal endoscopy. After surgery, radiotherapy or chemotherapy was used according to the patients’ condition. Results The CR rate of the observation group was 41.67%(χ^2=0.584,P=0.059), PR was 37.50%(χ^2=1.261, P=0.068), SD rate was 20.83%(χ^2=0.174, P=0.061), PD rate was 0.00%(χ^2=0.000,P=1.000). The incidence of adverse reaction was 50.00%(χ^2=0.855,P=0.095), and there was no significant difference between the two groups. Conclusion Nasal resection combined with nasal endoscopy for maxillary sinus carcinoma can effectively improve the long-term effect, prevent local recurrence and lymph node metastasis, and prolong the life span of patients.
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