重视妊娠期肝病的早期诊断  

Early diagnosis of liver disease during pregnancy should be taken seriously

作　　者：郑以山 ZHENG Yishan(Department of Critical Care Medicine,Nanjing Hospital Affiliated to Nanjing University of Chinese Medicine,Nanjing 210003,China)

机构地区：[1]南京中医药大学附属南京医院重症医学科

出　　处：《临床肝胆病杂志》2019年第7期1435-1438,共4页Journal of Clinical Hepatology

基　　金：江苏省十三五“科教强卫”卫生青年人才项目(QNRC2016056)

摘　　要：妊娠期适应性生理变化导致肝脏脆性增加,缓冲能力削弱,病程进展快;妊娠生理变化容易导致肝脏疾病信号或临床表现的掩盖,增加了早期诊断难度也容易延误治疗,增加治疗难度。但重症肝病是一个动态变化的过程,及时识别妊娠期肝病的早期信号,建立以大数据为基础的早期诊断和病情严重程度的评分系统,是确定妊娠期肝病诊断,治疗和判断分娩时机、方式的基础,也是提高妊娠期肝病治愈、降低病死率的关键。Adaptive physiological changes during pregnancy lead to increased fragility of the liver,impaired buffer capacity,and rapid disease progression,and such changes may weaken the signals or clinical manifestations of liver diseases,which increases the difficulties in early diagnosis and treatment. However,severe liver disease is a dynamic process,and timely identification of early signs of liver disease during pregnancy and establishment of early diagnosis and disease severity scoring system based on big data are the basis for determining the diagnosis and treatment of liver disease during pregnancy and deciding the timing and mode of delivery,as well as the key to improving the cure and reducing the mortality rate of liver disease during pregnancy.

关 键 词：肝疾病 妊娠 孕妇 诊断 

分 类 号：R575[医药卫生—消化系统] R714.25[医药卫生—内科学]