儿童期青光眼244例临床特征分析  

Clinical characteristics of 244 cases of childhood glaucoma

作　　者：黄洁蕾 陈翔熙 钟毅敏[1] 徐晓宇[1] 任丽蓉 刘杏[1] Huang Jie-lei;Chen Xiang-xi;Zhong Yi-min(Zhvngshan Ophthalmic Center, Sun Yat-sen University, Guang zhou 510060, China)

机构地区：[1]中山大学中山眼科中心

出　　处：《中国斜视与小儿眼科杂志》2019年第2期1-4,I0007,共5页Chinese Journal of Strabismus & Pediatric Ophthalmology

基　　金：中山大学临床医学研究5010计划资助(2014016);广东省科技计划项目(3030901005239)

摘　　要：目的分析儿童期青光眼的临床特征及表现。方法回顾性分析2005年1月至2014年12月在中山大学中山眼科中心青光眼区确诊并收入院的儿童期青光眼患者资料,对其视力、眼压、角膜直径及透明度、眼底C/D、眼轴长度进行分析及比较。结果 244例(404眼)儿童期青光眼中,原发性婴幼儿型青光眼占主要比例(213/404,52.72%),男女比例为1.62:1,双眼:单眼=1.90:1。所有患者平均眼压35.09±3.38(22~71)mmHg。共114眼配合视力检查。视力<0.05者33眼(28.9%),0.05~<0.3者32眼(28.1%),≥0.3的49眼(43%)。近视为不同类型儿童期青光眼患者的主要屈光状态。77.4%的婴幼儿型青光眼中角膜为中、重度水肿和混浊;62.5%的青光眼合并先天异常和50%的继发性青光眼角膜为重度水肿或者混浊。原发性婴幼儿型青光眼平均角膜横径为12.60±1.12mm,其平均角膜横径大于其他类型儿童期青光眼。结论儿童期青光眼其视力均较差,大部分是盲和低视力。各类型儿童期青光眼中,原发性婴幼儿型青光眼的平均角膜直径最大;青光眼合并先天异常的角膜混浊程度最重。Objective To evaluate the ocular manifestations of childhood glaucoma.Methods Patients with diagnosis of childhood glaucoma in Zhongshan Ophthalmic Center,Sun Yat-sen University from January 2005 to December 2014 were retrospectively studied.The visual acuity,intraocular pressure,corneal diameter and clarity,cup/disc ratio,axial lengths were analyzed and compared.Results Among 244 cases childhood glaucoma,primary infantile glaucoma was the most common subtype(213/404,52.72%).The male to female ratio was 1.62 : 1 and binocular to monocular ratio was1.90:1.114 eyes were measured visual acuity,among which 33 eyes(28.9%)had a visual acuity lower than 0.05,32 eyes(28.1%)had a visual acuity among 0.05 to 0.3 and 49 eyes(43%)better than 0.3.Myopia was the primary refractive status in all childhood glaucoma.The corneal clarity was moderate or severe edematous in primary infantile glaucoma(77.4%).,while which was severe edematous or cloudy in glaucoma associated with congenital anomalies and secondary glaucoma(62.5%,50%).The corneal diameter of primary infantile glaucoma was 12.60±1.12 mm,which was larger than other subtypes of childhood glaucoma.Conclusions The visual function of childhood glaucoma is quite poor and almost of all subtypes is clinically bind or low vision.Corneal diameter is largest in primary infantile glaucoma,while corneal opacity is heaviest in glaucoma associated with congenital anomalies.

关 键 词：儿童期青光眼 原发性先大性青光眼 

分 类 号：R775[医药卫生—眼科]