Caveolin-1基因的功能、多态性与疾病关系的研究进展  

Research progress on the relationship between the function,polymorphism of Caveolin-1 gene and clinical disease

作　　者：王佳美 刘欣跃[1] WANG Jiamei;LIU Xinyue(Laboratory Medical Center,Lanzhou University Second Hospital,Lanzhou,Gansu 730030,China)

机构地区：[1]兰州大学第二医院检验医学中心

出　　处：《国际检验医学杂志》2019年第14期1762-1766,共5页International Journal of Laboratory Medicine

基　　金：甘肃省卫生行业科研计划项目(GSWSKY2017-31);兰州大学第二医院2015年度第一批院内博士基金(ynbskyjj2015-1-03)

摘　　要：Caveolin-1 (CAV-1)是一种膜标记性蛋白,对调节细胞内外环境稳态起着重要的作用。近年来,对其编码基因CAV-1的研究逐渐成为热点,该文旨在综述CAV-1的结构、功能、基因多态性与临床疾病易感性的关系,以期提高临床对CAV-1的认识。Caveolin-1 (CAV-1) is a marker protein of membrane,which plays an important role in regulating homeostasis of intracellular and extracellular environment.In recent years,the research on the encoding gene of CAV-1 has become a hot topic.The purpose of this review is to summarize the characteristics of CAV-1 gene,and describe the relationship with susceptibility to clinical diseases,to make further efforts to understanding of CAV-1.

关 键 词：CAVEOLIN-1 基因多态性 疾病易感性 

分 类 号：R735.1[医药卫生—肿瘤]