Hyperbranched polylysine:Synthesis,mechanism and preparation for NIR-absorbing gold nanoparticles  

作　　者：Yiying Ge Pan Li Yanfei Guan Chang-Ming Dong 

机构地区：[1]School of Chemistry and Chemical Engineering, Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University

出　　处：《Chinese Chemical Letters》2019年第7期1428-1431,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (No. 21474061);the Innovation Program ofShanghai Municipal Education Commission (No. 201701070002E0061);the Innovation Fund (No. IFPM2016B004) of Shanghaijiao Tong University & Affiliated Sixth People’s Hospital South Campus are appreciated

摘　　要：The ring-opening polymerization (ROP) of N-(tetrafluoroboran ammonium)-L-lysine-N-carboxyanhydride (NH3BF4-Lys NCA) was initiated by triethylamine to prepare hyperbranched polylysine (HPlys) fluoroborate with narrow polydispersity at a low temperature. Both mass spectroscopy analysis and DFT computation evidenced that the resultant cyclic dimer mainly initiated ROP as a secondary species according to normal amine mechanism. The hyperbranched polylysine in aqueous solution existed in a unimolecular state at low concentrations, but transformed into spherical micellar aggregates at a high concentration of 5 mg/mL, as characterized by dynamic laser scattering and transmission electron microscopy. By utilizing multivalent coordination interactions between hyperbranched polylysine and gold, the plasmonic gold nanoparticles (HPlys@Au NPs) were successfully prepared in aqueous solution, which elevated the solution by 23.1℃ upon 5 min of NIR laser irradiation (808 nm, 2 W/cm2).The ring-opening polymerization（ROP）of N-（tetrafluoroboran ammonium）-L-lysine-N-carboxyanhydride（NH3 BF4-Lys NCA）was initiated by triethylamine to prepare hyperbranched polylysine（HPlys）fluo robo rate with narrow polydispersity at a low temperature.Both mass spectroscopy analysis and DFT computation evidenced that the resultant cyclic dimer mainly initiated ROP as a secondary species according to normal amine mechanism.The hyperbranched polylysine in aqueous solution existed in a unimolecular state at low concentrations,but transformed into spherical micellar aggregates at a high concentration of 5 mg/mL,as characterized by dynamic laser scattering and transmission electron microscopy.By utilizing multivalent coordination interactions between hyperbranched polylysine and gold,the plasmonic gold nanoparticles（HPlys@Au NPs）were successfully prepared in aqueous solution,which elevated the solution by 23.1 ℃ upon 5 min of NIR laser irradiation（808 nm,2 W/cm2）.

关 键 词：HYPERBRANCHED POLYLYSINE NCA ROP NIR Gold nanoparticles 

分 类 号：O6[理学—化学]