supported by the National Natural Science Foundation of China(Nos.82370977,52073186);Medical Science and Technology Project of Sichuan Provincial Health Commission(No.21PJ059);Science and Technology Application Fundamental Project of Sichuan Province(No.2022YFS0124);Funding for Distinguished Young Scholars of Sichuan Province(No.23NSFJQ0001);Strategic Cooperation Projects of Yi Bin City and Sichuan University(No.2020CDYB-6)。
Infections frequently occur after skin injuries,posing a significant challenge in current clinical care.Frequently changing dressings to minimize wound infections and adhesions results in large amounts of medical wast...
supported by the Natural Science Foundation of Anhui Province,China(Grant No.2208085MB32);the Anhui Provincial Program on Key Research and Development Project,China(Grant No.202004a06020021);the Key Research Program on Natural Science of Anhui Higher Education,China(Grant No.KJ2020A0049);the National Natural Science Foundation of China(Grant No.21606002);the Undergraduate Research Training Program for Innovation(Grant No.202210357050).
Liquid fermented fungal mycelia with decolorization capability have potential applications in scale-up. In this work, the Lactarius deliciosus mycelia were immobilized on ε-polylysine-alginate beads, and the decolori...
supported by the Natural Science Foundation of Jiangsu Province (BK20210016);the National Key R&D Program of China (2020YFA0710800);the Key Program of National Natural Science Foundation of China (grant no.81930043);the Major International (Regional)Joint Research Project of China (grant no.81720108020);the Jiangsu Provincial Key Research and Development Program (BE2020621).
Poly-L-lysine(PLL)is a water-soluble biopolymer consist of repeating unit of L-lysine.It displays intrinsic non-antigenicity,antibacterial property,biocompatibility,and biodegradability,and facile synthesis procedure,...
This study aimed to evaluate the antibacterial effects of ε-polylysine (ε-PL) and plant extracts of Thymus vulgaris, Zataria multiflora, and Salvia verticillata against the spoilage bacterium Pseudomonas aeruginosa ...
financially supported by National Key Research and Development Project of China (No. 2021YFB4001101);the National Natural Science Foundation (NSFC) of China (No.22075176);Natural Science Foundation of Shanghai (No.22ZR1429200);NSFC projects (Nos. 51833006, 82071160,81870806 and 81974152)
Commercial tissue adhesives have been widely applied in wound hemostats and dressings while enhancing the hemostasis and healing capabilities is challenging to meet clinical needs.Herein,we designed the glucose-and ca...
This work was supported by the National Natural Science Foundation of China(Grant No.31871830);Natural Science Foundation of Zhejiang Province,China(Grant No.LY18C200002);Key research and development program of Zhejiang Province,China(Grant No.2019C02088);and Food Science and Engineering,the most important discipline of Zhejiang Province,China(Grant No.2017SIAR217).
In order to solve the problems of poor oil solubility of epsilon-polylysine(ε-PL)and the resulting poor antimicrobial performance,a water-in-oil(W/O)microemulsion containingε-PL was constructed by drawing a pseudo t...
National Natural Science Foundation of China(Grant No.51773018,51973018);Key Research and Development Projects of People’s Liberation Army(BWS17J036).
Cell transplantation is an effective strategy to improve the repair effect of nerve guide conduits(NGCs).However,problems such as low loading efficiency and cell anoikis undermine the outcomes.Microcarriers are effici...
the National Natural Science Foundation of China(Nos.51773201 and 51973212);the Bureau of Science and Technology of Changchun(No.19SS005);the Department of Science and Technology of Jilin Province(No.20200301017RQ);the Joint Program of CAS-Jilin Province(No.2019SYHZ0002).
Medical devices-related infections pose a great threat to patients and cause an increased morbidity and mortality. Herein, we prepare an antibacterial composite(TPU-x) through blending medical grade thermoplastic poly...
the National Natural Science Foundation of China(No.51873208);the National Science and Technology Major Projects for Major New Drugs Innovation and Development(No.2018ZX09711003-012);National Program for Support of Top-notch Young Professionals,Jilin Province Science and Technology Development Program(No.20180414027GH)for financial support to this work。
A novel amphiphilic cationic block copolymer polylysine-b-polyphenylalanine(PLL-b-PPhe)was synthesized and self-assembled into micelles in aqueous solution,then shielded with poly(glutamic acid)(marked as PG/PLL-b-PPh...
supported by the National Natural Science Foundation of China (No. 21474061);the Innovation Program ofShanghai Municipal Education Commission (No. 201701070002E0061);the Innovation Fund (No. IFPM2016B004) of Shanghaijiao Tong University & Affiliated Sixth People’s Hospital South Campus are appreciated
The ring-opening polymerization (ROP) of N-(tetrafluoroboran ammonium)-L-lysine-N-carboxyanhydride (NH3BF4-Lys NCA) was initiated by triethylamine to prepare hyperbranched polylysine (HPlys) fluoroborate with narrow p...