BIOMEDICINE

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Advances and applications of genome-edited animal models for severe combined immunodeficiency
《Zoological Research》2025年第1期249-260,共12页Xiao Zheng Chun-Hui Huang Sen Yan Ming-Deng Rong 
supported by the Postdoctoral Fellowship Program of CPSF (GZC20231064);China Postdoctoral Science Foundation (2024M761345);Guangzhou Basic and Applied Basic Research Foundation (2024A04J6615);Scientific Research Project of Southern Medical University Stomatological Hospital (PY2023004);National Key Research and Development Program of China (2021YFA0805300);National Natural Science Foundation of China (82171244,32470564)。
Severe combined immunodeficiency disease(SCID),characterized by profound immune system dysfunction,can lead to life-threatening infections and death.Animal models play a pivotal role in elucidating biological processe...
关键词：Gene-editing technology Animal model Translational biomedicine Severe combined immunodeficiency disease 
Near-infrared carbon dots:pioneering emerging frontiers in biomedical applications
《新型炭材料(中英文)》2025年第1期131-153,共23页HE Qian YANG Yan-li LI Rui-jiao MA Dan ZHANG Li-yun 
financial support by Talent Introduction Research Initiation Fund of Shanxi Bethune Hospital(2022RC04);Basic Research Program Youth Science Research Project of Shanxi province(202203021212096);Shanxi Province Clinical Theranostics Technology Innovation Center for Immunologic and Rheumatic Diseases(CXZX-202302);Research Project Plan of Shanxi Provincial Administration of Traditional Chinese Medicine(2023ZYYB2021)。
Carbon dots(CDs)are fluorescent carbon-based nanomaterials with sizes smal-ler than 10 nm,that are renowned for their exceptional properties,including superior anti-photobleaching,excellent biocompatibility,and minima...
关键词：Near-infrared carbon dots BIOIMAGING BIOSENSING Therapy BIOMEDICINE 
Biofabrication:Bioprinting Process,Printing Materials,and the Frontier Applications in Biomedicine
《Additive Manufacturing Frontiers》2024年第4期102-114,共13页Yuxiang Qin Linlin Fan Lei Zhan Jiayi Sun Jianhong Liu Canyu Gao Sisi Ma Xiaobing Pu Li Zhao Ying Zheng Lihua Jiang Changchun Zhou Yujiang Fan 
supported by National Key Research and Development Program of China(Grant Nos.2023YFC2411300,2023YFB4605800);National Natural Science Foundation of China(Grant No.32471474);Sichuan Science and Technology Program(Grant Nos.2024YFHZ0125,2022NSFSC1405);China Postdoctoral Science Foundation(Grant No.2022M722268);Research and Develop Program,West China Hospital of Stomatology Sichuan University(Grant No.RD-03-202406).
Biofabrication,also known as bioprinting,has been widely used in the field of biomedicine.The three most important factors in biofabrication are 3D bioprinter,biomaterials to be printed(bioinks),and the printing objec...
关键词：BIOFABRICATION Bioprinting process Printing materials Frontier applications 
Animal models in neuroscience with alternative approaches:Evolutionary,biomedical,and ethical perspectives
《Animal Models and Experimental Medicine》2024年第6期868-880,共13页Sabina Neziri Ahmet Efe Köseoğlu Gülsüm Deniz Köseoğlu BuminhanÖzgültekin NehirÖzdemirÖzgentürk 
Animal models have been a crucial tool in neuroscience research for decades,providing insights into the biomedical and evolutionary mechanisms of the nervous system,disease,and behavior.However,their use has raised co...
关键词：alternatives animal models BIOMEDICINE ETHICS evolution NEUROSCIENCE 
Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks
《Asian Journal of Pharmaceutical Sciences》2024年第6期21-47,共27页Yuanke Zhang Lvyao Yang Min Zhou Yanhua Mou Dongmei Wang Peng Zhang 
Overcoming the poor physicochemical properties of pure alginate gel and the inherent shortcomings of pure metal-organic framework(MOF),alginate/MOF composite gel has captured the interest of many researchers as a tuna...
关键词：ALGINATE Metal-organic framework(MOF) In-situ generation Chelation mechanism BIOMEDICINE 
《Journal of Zhejiang University-SCIENCE B(Biomedicine & Biotechnology)》 Total contents
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第12期I0002-I0009,共8页
Lensless fiber endomicroscopy in biomedicine
《PhotoniX》2024年第1期402-410,共9页Jiawei Sun Robert Kuschmierz Ori Katz Nektarios Koukourakis Juergen W.Czarske 
organized by Projekt DEAL.German Research Foundation(DFG)grant CZ55/40,CZ55/47;European Research Council(ERC)Horizon 2020 research and innovation program(grant no.101002406);Shanghai Artificial Intelligence Laboratory,National Key R&D Program of China(2022ZD0160100);Else Kroner Fresenius Center for digital Heath(EKFZ)and Competence Center for Biomedical Computational Laser Systems(BIOLAS).
Lensless fiber endomicroscopy,an emergent paradigm shift for minimally-invasive microscopic optical imaging and targeted light delivery,holds transformative potential,especially in biomedicine.Leveraging holographic d...
关键词：Lensless endomicroscope Biomedical imaging Multimode fibers Multicore fibers Translation to real-world applications 
Research advances of tetrahedral framework nucleic acid-based systems in biomedicine
《Chinese Chemical Letters》2024年第11期35-43,共9页Lihang Wang Mary Li Javier Chunshan Luo Tingsheng Lu Shudan Yao Bing Qiu Yun Wang Yunfeng Lin 
supported by National Key R&D Program of China(No.2019YFA0110600);National Natural Science Foundation of China(Nos.82370929,81970916);Sichuan Science and Technology Program(No.2022NSFSC0002);Sichuan Province Youth Science and Technology Innovation Team(No.2022JDTD0021);Research and Develop Program,West China Hospital of Stomatology Sichuan University(No.RD03202302);Science and technology support plan project of Guizhou Provincial Department of science and technology(No.Qiankehe support[2022]General264)。
This article reviews the latest research advances of tetrahedral framework nucleic acid(t FNA)-based systems in their fabrication,modification,and the potential applications in biomedicine.TFNA arises from the synthes...
关键词：DNA nanomaterials Tetrahedral framework nucleic acid Drug delivery ANTIOXIDATION IMMUNOMODULATION Tissue regeneration Antitumor therapy 
Special Issue on Autism:from Bench to Bedside Journal of Zhejiang University-SCIENCE B(Biomedicine&Biotechnology)| Volume 25,Issue 11,2024
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第11期I0001-I0001,共1页
Cover Story Autism spectrum disorder(ASD)is a complex neurodevelopmental condi-tion,characterized by social communication deficits,restrictive behaviors,and repetitive interests.Despite significant advances,the puzzle...
关键词：diagnosis offering SPITE 
Metal organic framework modulated nanozymes tailored with their biomedical approaches
《Chinese Chemical Letters》2024年第11期155-171,共17页Manoj Kumar Sarangi L.D Patel Goutam Rath Sitansu Sekhar Nanda Dong Kee Yi 
Nanozymes are the paradigm for bridging inorganic nanomaterials with biology and environment for taking the spontaneous responsibilities to outplay natural enzymes.Metal-organic frameworks(MOFs) are mesoporous materia...
关键词：MOF Nanozyme CATALYSIS BIOMEDICINE THERANOSTICS 
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