肝硬化与肝癌癌前病变的研究进展  

Advances in the study of cirrhosis and precancerous lesions of liver cancer

作　　者：吴东波[1] 唐红[1] Wu Dongbo;Tang Hong(Center of Infectious Diseases,West China Hospital of Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院感染性疾病中心,成都610041

出　　处：《中华肝脏病杂志》2019年第7期483-486,共4页Chinese Journal of Hepatology

基　　金：国家自然科学基金(81772193).

摘　　要：肝硬化是一种常见的慢性肝病,随着疾病发展,部分患者可逐渐出现癌前病变、甚至进展为肝细胞癌(HCC)。肝脏的癌前病变主要包括异型增生灶和异型增生结节,且大多数发生在肝硬化的基础之上。通过增强对肝硬化及癌前病变的认识,加强对肝硬化患者的筛查,结合影像学及病理学的特点,积极鉴别肝硬化结节的性质,正确诊断癌前病变与HCC,将有助于提高癌前病变及早期HCC的确诊率,改善患者的临床预后。Liver cirrhosis is a common kind of chronic liver diseases, with the development of diseases;some patients may gradually develop precancerous lesions, or even progress to hepatocellular carcinoma (HCC). Precancerous lesions of the liver mainly include dysplastic foci (DF) and dysplastic nodules (DN), and most of it occurs on the basis of liver cirrhosis. Thus, recognition of precancerous lesions and liver cirrhosis through screening, combined with imaging and pathological features will identity the nature of nodules in early stage cirrhosis and HCC, and thereby will help to improve the diagnosis rate and clinical prognosis.

关 键 词：肝硬化 癌 肝细胞 癌前病变 

分 类 号：R575.2[医药卫生—消化系统]