脑白质疏松与认知功能障碍的关系研究  

A study on the relationship between white matter loosening and cognitive dysfunction

作　　者：吴贤丽 李先锋[1] 吴育朗[1] 谢兴锐 范利齐 WU Xian-li;LI Xian-feng;WU Yu-lang(The First People's Hospital of Nanning, Nanning, 530022,China)

机构地区：[1]南宁市第一人民医院

出　　处：《吉林医学》2019年第8期1718-1720,共3页Jilin Medical Journal

摘　　要：目的:探讨分析脑白质疏松与认知功能障碍的关系。方法:选取50例患者,根据脑CT/MRI分为脑白质疏松(LA)组和对照组,每组25例。用简易精神状态量表(MMSE)进行评分,依据Aharon-Peretz标准对LA程度进行分级,然后比较两组患者的MMSE评分的均数和认知功能障碍的发生率,探索LA级数与认知障碍程度的相关性。结果:对照组患者MMSE评分明显高于LA组,对照组认知功能障碍发生率低于LA组,LA级数和认知障碍程度呈线性相关,相关系数TS=0.903,具有统计学联系。结论:LA是认知功能障碍的其中一个原因,LA级数与认知功能障碍程度呈线性相关。Objective To investigate the relationship between leukoplast and cognitive dysfunction. Method 50 patients were selected.According to the cerebral CT/MRI, they were divided into cerebral leukoplast(LA) and control groups.In each group, 25 cases were scored using the simple mental state scale(MMSE) and the LA level was graded according to the Aharon-Peretz standard., Then the MMSE score and the incidence of cognitive dysfunction were compared between the two groups.Explore the correlation between the LA series and the degree of cognitive impairment. Results The MMSE score was significantly higher in the control group than in the LA group, the incidence of cognitive dysfunction in the control group was lower than in the LA group, and the LA level was linearly related to the degree of cognitive impairment.The correlation coefficient TS = 0.903 was statistically related. Conclusion LA is one of the causes of cognitive dysfunction.The LA series is linearly related to the degree of cognitive dysfunction.

关 键 词：脑白质疏松 认知功能障碍 精神状态检查表 MMSE 

分 类 号：R742[医药卫生—神经病学与精神病学] R749.1[医药卫生—临床医学]