孕中期18-三体综合征胎儿结构异常声像图分析  

Ultrasonography analysis of fetus structure abnormality with trisomy 18 syndrome at middle pregnancy

作　　者：邓凤莲 段灵敏 郭燕丽 薛雅方 刘建君 王琰 陈颖 DENG Fenglian;DUAN Lingmin;GUO Yanli;XUE Yafang;LIU Jianjun;WANG Yan;CHEN Ying(Department of Ultrasound,the First Hospital Affiliated to Army Medical University/Southwest Hospital,Chongqing 400038,China)

机构地区：[1]陆军军医大学第一附属医院/西南医院超声科

出　　处：《重庆医学》2019年第14期2373-2376,共4页Chongqing medicine

基　　金：“十二五”国家科技支撑计划项目(2014BA106B00)

摘　　要：目的探讨产前超声在孕中期18-三体综合征胎儿诊断价值。方法回顾性分析经羊膜腔穿刺、脐血管穿刺胎儿染色体确诊中孕期18-三体综合征胎儿17例的临床资料和超声影像特征。结果 17例18-三体综合征胎儿中孕期超声声像图表现有2~10项不等的异常声像,其中4项及以上超声异常者占94.1%。最常见的超声异常为心脏畸形[17(100.0%)],其次为颅脑畸形[15(88.2%)]、颜面部异常[12(70.6%)]和四肢畸形[7(41.2%)]。结论产前系统超声检查对提高18-三体综合征的产前检出率具有重要意义。Objective To explore the diagnostic value of prenatal ultrasound in middle pregnancy of trisomy 18 syndrome. Methods The clinical data and ultrasonographic features of 17 cases of trisomy 18 syndrome in pregnancy by amniocentesis and umbilical vascular puncture were confirmed retrospectively. Results Ultrasound sonograms of 17 cases of trisomy 18 syndrome in the fetus had 2 to 10 abnormal sound images.There were 94.1% having more than 4 images.The most common ultrasound abnormalities were cardiac malformation [17(100.0%)],followed by brain malformation [15(88.2%)],facial abnormalities [12( 70.6 %)] and limb deformity [7(41.2%)]. Conclusion Prenatal ultrasonography has great significance to improve the prenatal detection rate of trisomy 18 syndrome.

关 键 词：超声检查 产前 18-三体综合征 产前诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学]