Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882  

作　　者：Lin Peng Tao Ning Wenbo Lu Peizhang Chen Haifeng Li Yanjie Yi Zichao Wang Yuansen Hu 

机构地区：[1]National Engineering Laboratory for Cereal Fermentation Technology,Jiangnan University,Wuxi 214122,China [2]College of Biological Engineering,Henan University of Technology,Zhengzhou 450001,China

出　　处：《Grain & Oil Science and Technology》2019年第1期11-14,共4页粮油科技（英文版）

基　　金：supported by the Natural Science Foundation of Youth Support Plan of Henan University of Technology (2017QNJH10);High Level Research Fund for Qualified People of Henan University of Technology (2017BS011);the Natural Science Foundation of Henan Province Education Department (19A180015)

摘　　要：Polysaccharide produced from medicinal endophytic fungus not only has applications in foods,but also exhibits multiple biological activities.In this work,an endophytic fungus Chaetomium globosum CGMCC 6882 could use corn stover to produce a polysaccharide(GCP-SC)by consolidated bioprocess and the titer of GCP-SC reached 3.2 g/L.The transcriptional levels of genes related to cellulose degradation(cbh,cdh,glu and egl)in C.globosum CGMCC 6882 were 4.38,3.85,3.13,and 2.17 folds compared to the control group when corn stover was used as the sole carbon source.Moreover,GCP-SC showed a time-and dose-dependent manner of inhibitory effect on A549 cells and the inhibitory rate reached 93.3%.This work provides meaningful data on agricultural residues utilization and facilitation of future relative resource conversion studies.Polysaccharide produced from medicinal endophytic fungus not only has applications in foods, but also exhibits multiple biological activities. In this work, an endophytic fungus Chaetomium globosum CGMCC 6882 could use corn stover to produce a polysaccharide (GCP-SC) by consolidated bioprocess and the titer of GCP-SC reached 3.2 g/L. The transcriptional levels of genes related to cellulose degradation (cbh, cdh, glu and egl) in C. globosum CGMCC 6882 were4.38, 3.85, 3.13, and 2.17 folds compared to the control group when corn stover was used as the sole carbon source.Moreover, GCP-SC showed a time-and dose-dependent manner of inhibitory effect on A549 cells and the inhibitory rate reached 93.3%. This work provides meaningful data on agricultural residues utilization and facilitation of future relative resource conversion studies.

关 键 词：CORN STOVER CHAETOMIUM globosum CGMCC 6882 POLYSACCHARIDE 

分 类 号：TS[轻工技术与工程]