原发性腹膜后脂肪肉瘤的诊治分析  

Diagnosis and treatment of primary retroperitoneal liposarcoma

作　　者：任项项 刘钢山 吴硕东[1] 田雨[1] Ren Xiangxiang;Liu Gangshan;Wu Shuodong;Tian Yu(Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China)

机构地区：[1]中国医科大学附属盛京医院,沈阳110004

出　　处：《中华普通外科杂志》2019年第7期576-579,共4页Chinese Journal of General Surgery

摘　　要：目的探讨原发性腹膜后脂肪肉瘤的临床特点、诊断、治疗及预后。方法回顾性分析2008年1月至2018年6月中国医科大学附属盛京医院收治的经术后病理检查证实的44例原发性腹膜后脂肪肉瘤患者的临床资料。结果44例原发性腹膜后脂肪肉瘤患者的临床表现主要为腹部包块、腹胀伴腹痛,无症状者主要为体检发现。术前CT检查为主要检查手段,准确率为75%。术后病理类型主要为高分化脂肪肉瘤。随访期间44例患者中36例(82%)出现复发,24例(55%)死于肿瘤复发,2例死于其他疾病。结论原发性腹膜后脂肪肉瘤在早期难以被发现,CT是该病主要的检查手段,完整的手术切除是初发和再次复发的主要治疗方法。该病易复发,预后差。Objective The aim of this study is to analyze the clinical characteristics, diagnosis, treatment and prognosis factors of primary retroperitoneal liposarcoma. Methods We retrospectively analyzed 44 patients diagnosed with primary retroperitoneal liposarcoma that confirmed by pathology from Jan 2008 to Jun 2018 at the Department of General Surgery, Shengjing Hospital, China Medical University. Results The 44 patients consist of 19 males and 25 females, the clinical manifestations were abdominal mass, abdominal distension and abdominal pain. Asymptomatic patients were mainly found through physical examination. The main preoperative examination method was CT, and its accuracy rate was 75%. The most common pathological type was well-differentiated liposarcoma. The recurrence rate is 82%, and 24 (55%) patients died from tumor recurrence, 2 patients died of other unrelated diseases. Conclusions Primary retroperitoneal liposarcoma is difficult to be diagnosed at early stage. CT is the main examination method. Complete surgical resection is the main treatment for primary or recurrent patients. This disease is prone to relapse and the prognosis is poor.

关 键 词：脂肪肉瘤 腹膜后肿瘤 外科手术 

分 类 号：R735.4[医药卫生—肿瘤]