羟考酮联合腕踝针治疗肺癌骨转移疼痛  

Treatment of Bone Metastasis Pain from Lung Cancer with Hydroxycodone Combined with Wrist-ankle Needle

作　　者：刘玮 孙炜 王莉 臧建华 段茜 方超 蒋慧 LIU Wei;SUN Wei;WANG Li;ZANG Jianhua;DUAN Qian;FANG Chao;JIANG Hui(Department of Oncology,Qingdao Haici Medical Group,Qingdao 266033,Shandong Province,China;Department of Acupuncture and Rehabilitation,Qingdao Haici Medical Group,Qingdao 266033,Shandong Province,China;Department of Nursing,Qingdao Haici Medical Group,Qingdao 266033,Shandong Province,China)

机构地区：[1]青岛市海慈医疗集团肿瘤科,山东青岛266033 [2]青岛市海慈医疗集团针推康复科,山东青岛266033 [3]青岛市海慈医疗集团护理部,山东青岛266033

出　　处：《吉林中医药》2019年第7期911-914,共4页Jilin Journal of Chinese Medicine

基　　金：山东省中医药科技发展计划项目(2017-325);青岛市2016年度医药科研指导计划(2016-WJZD025)

摘　　要：目的探究腕踝针联合盐酸羟考酮治疗肺癌骨转移中重度疼痛患者的临床效果及对生存质量的影响。方法将83例中重度肺癌骨转移疼痛患者分为对照组与研究组。对照组40例,行盐酸羟考酮治疗;研究组43例,行腕踝针联合盐酸羟考酮治疗。观察2组镇痛起效时间及持续时间、疼痛评分、疼痛缓解效果、生存质量、不良反应发生率。结果研究组平均镇痛起效时间短于对照组,平均镇痛持续时间长于对照组(P<0.05)。治疗3周后,研究组NRS评分、疼痛症状、失眠评分均低于对照组,躯体功能、整体生存质量高于对照组(P<0.05)。研究组疼痛缓解总有效率高于对照组,不良反应发生率低于对照组(P<0.05)。结论腕踝针联合盐酸羟考酮治疗中重度肺癌骨转移疼痛起效快,疼痛缓解效果理想。Objective To investigate the clinical effect of wrist-ankle acupuncture combined with oxycodone hydrochloride in the treatment of severe pain patients with bone metastases from lung cancer and its effect on quality of life. Methods Eighty-three patients with bone metastasis from moderate to severe lung cancer were divided into two groups. The control group(40 cases) was treated with oxycodone hydrochloride, and the study group(43 cases)was treated with wrist-ankle acupuncture combined with oxycodone hydrochloride. The onset time and duration of analgesia, pain score, pain relief effect, quality of life and adverse reaction rate were observed. Results The average onset time of analgesia in the study group was shorter than that in the control group, and the average duration of analgesia was longer than that in the control group(P < 0.05). After 3 weeks of treatment, NRS scores, pain symptoms and insomnia scores of the study group were lower than those of the control group, while physical function and overall quality of life of the study group were higher than those of the control group(P < 0.05). The total effective rate of pain relief in the study group was higher than that in the control group, and the adverse reaction rate was lower than that in the control group(P < 0.05). Conclusion Wrist-ankle acupuncture combined with oxycodone hydrochloride in the treatment of bone metastasis pain of moderate and severe lung cancer has a quick effect, and the pain relief effect is ideal.

关 键 词：腕踝针 盐酸羟考酮 肺癌 骨转移 疼痛 

分 类 号：R734.2[医药卫生—肿瘤]