低温等离子消融术治疗早期声门型喉癌的临床分析  

Clinical analysis of radiofrequency ablation in the treatment of early glottic carcinoma under laryngoscope

作　　者：张纪勇 王启威[1] 赵剑南[1] 周晓杰 李慧军[1] ZHANG Ji-yong;WANG Qi-wei;ZHAO Jian-nan;ZHOU Xiao-jie;LI Hui-jun(Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of HarbinMedical University, Harbin 150001, China)

机构地区：[1]哈尔滨医科大学附属第一医院耳鼻咽喉头颈外科

出　　处：《哈尔滨医科大学学报》2019年第3期265-268,共4页Journal of Harbin Medical University

摘　　要：目的探讨支撑喉镜下等离子手术对于Tis T1 T2声门型喉癌在局部控制、生存率以及喉功能保留上的效果。方法回顾性分析自2012年10月~2016年6月89例支撑喉镜下行等离子手术的早期声门型喉鳞状细胞癌的患者,计算患者生存率、局部控制率、喉保存率并对相关因素进行分析。结果生存率为96%(86/89)(1例患者因肺大细胞癌骨转移死亡),局部复发率为10%(9/89),其中Tis局部无复发;T1a复发率为3%(2/58)、T1b为23%(4/17)、T2为30%(3/10),喉保存率为91%(81/89)。T1b及T2型患者复发率与T1a型患者复发率3%(3/58)之间差异明显。结论低温等离子射频消融治疗早期声门型喉癌并发症少,局部控制率高及喉功能保全良好,为早期喉鳞状细胞癌的治疗方案之一。Objective To explore the effects of plasma surgery under laryngoscope on local control, survival and laryngeal function of Tis T1 T2 glottic carcinoma. Methods A retrospective analysis of 89 patients with early glottic laryngeal carcinoma who underwent direct laryngoscope plasma surgery from October 2012 to June 2016 was performed to calculate patient survival ,local control rate, laryngeal preservation rate, and related factors. Results The survival rate was 96%(86/89)(1 patient died from bone metastasis of lung cancer), and the local recurrence rate was 10%( 9/89 ), and there was no recurrence of Tis. The recurrence rate of T1 a was 3%(2/58 ), T1 b was 23%(4/17), T2 was 30%(3/10), and the retention rate was 91 %(81/89). The recurrence rate of T1 b and T2 patients was significantly different with the recurrence rate of T1 a patients which was 3%(2/58). Conclusion Coblation radiofrequency ablation is one of treatment options for early laryngeal carcinoma with low complication rate, high local control rate and good laryngeal function preservation.

关 键 词：射频消融术 声门型喉癌 喉镜检查 

分 类 号：R739.65[医药卫生—肿瘤]