调强放疗时代头颈部肿瘤腮腺组织损伤的认识及研究进展  

Understanding and Research Progress of Parotid Gland Tissue Injury in Patients with Head and Neck Cancer in the Era of Intensity-Modulated Radiotherapy

作　　者：岑妍芳(综述) 李媛媛 金风(审校) Cen Yanfang;Li Yuanyuan;Jin Feng(Department of Oncology, School of Clinical Medicine, Guizhou Medical University, Guiyang 550001 ,Guizhou, China;Department of Head and Neck Oncology, The Affiliated Hospital of Guizhou Medical University, Guizhou Cancer Hospital, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang 550001 , Guizhou, China)

机构地区：[1]贵州医科大学临床医学院肿瘤学教研室,贵阳550001 [2]贵州医科大学附属医院·贵州省肿瘤医院头颈肿瘤科

出　　处：《肿瘤预防与治疗》2019年第7期638-644,共7页Journal of Cancer Control And Treatment

基　　金：贵州省科技基金项目(编号:黔科合LG字[2012]001号)~~

摘　　要：腮腺的放射性损伤是头颈部肿瘤放疗最常见的并发症之一。调强适形放射治疗较常规放疗对腮腺有更好的保护作用,但腮腺的放射性损伤不可避免。在调强时代如何动态评估放射治疗中腮腺的变化及以更优化的方案防护腮腺功能值得探讨。本文就近年来调强放射治疗对头颈部肿瘤患者腮腺影响的相关研究及进展作一综述。Radiation-induced injury of parotid glands is one of the most common complications of radiotherapy for head and neck tumors. Compared with conventional radiotherapy, intensity-modulated radiation therapy (IMRT) has a more protective effect on the parotid glands. However, radiation-induced injury of parotid glands remains inevitable in IMRT. It is desirable to explore how to dynamically evaluate the changes in parotid glands during radiotherapy, and to develop optimized schemes to protect the parotid function. This paper reviews the recent studies of and advances in the effects of IMRT on parotid glands of patients with head and neck tumors.

关 键 词：调强放射治疗 头颈部肿瘤 腮腺损伤 

分 类 号：R739.91[医药卫生—肿瘤] R730.55[医药卫生—临床医学]