食管癌患者孤立性肺结节性质与其原发肿瘤的关系分析  

Study on relationship between properties of solitary pulmonary nodules and primary tumor in patients with esophageal cancer

作　　者：宋帅[1] 常栋[1] 崔永[1] 高志[1] 刘春全[1] 李浩[1] 胡健[1] 王天佑[1] SONG Shuai;CHANG Dong;CUI Yong(Department of Thoracic Surgery,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院胸外科

出　　处：《临床和实验医学杂志》2019年第16期1751-1754,共4页Journal of Clinical and Experimental Medicine

基　　金：吴阶平医学基金会临床科研专项资助基金(编号:320.6750.18475)

摘　　要：目的探讨食管癌患者孤立性肺结节性质与其原发肿瘤的相关性。方法回顾性分析2012年1月至2018年12月首都医科大学附属北京友谊医院胸外科收治的食管癌患者,统计分析同期行手术切除的食管癌合并肺内孤立性结节患者的病例资料,评价肺部结节性质与其原发肿瘤的相关性。结果共回顾性调查同期行手术切除的食管癌合并肺内孤立性结节患者23例。胸部增强CT检查显示,结节位于左肺者15例,位于右肺者8例。结节大小为0.4~3.0 cm,其中≤1 cm者14例,>1 cm者9例。病理结果显示,肺内结节良性病变18例,其中炎性组织13例,纤维组织2例,胶原变性1例,结核2例;恶性病变5例,均为原发性肺腺癌,没有发现食管转移癌。结论在缺乏全身多发转移的情况下,食管癌患者的肺内孤立性结节很少是食管肿瘤的肺部转移,更多为良性结节或是肺内原发肿瘤。Objective To explore the relationship between properties of solitary pulmonary nodules and primary tumor in patients with esophageal cancer.Methods Retrospective analysis on the clinical features of patients with esophageal cancer in this hospital during January 2012 to December 2018.The clinical data of patients with esophageal cancer and solitary pulmonary nodules underwent concurrent surgery were stastically analyzed.To assess the correlation between the pathological properties of pulmonary nodules and primary tumors.Results A total of 23 patients underwent surgical resection of esophageal cancer and solitary pulmonary nodules.Chest-enhanced CT findings showed that 15 patients had nodules in the left lung and 8 patients in the right lung.The size of nodules was 0.4-3.0 cm,of which 14 cases were less than or equal to 1 cm and9 cases were larger than 1 cm.Pathological results showed that there were 18 cases of benign pulmonary nodules,including 13 cases of inflammatory tissue,2 cases of fibrous tissue,1 case of collagen degeneration,2 cases of tuberculosis;5 cases of malignant lesions,all of them were primary lung adenocarcinoma.There was no esophageal metastasis nodules.Conclusion In the absence of extra-pulmonary metastasis,solitary pulmonary nodules in patients with esophageal cancer are extremely unlikely to be metastatic esophageal cancer.These nodules are more likely to be benign nodules or primary lung cancers.

关 键 词：食管癌 孤立性肺结节 肺转移 

分 类 号：R735.1[医药卫生—肿瘤]