青年和老年急性胰腺炎对比观察及危险因素分析  

Comparative observation and risk factors analysis of acute pancreatitis in young and old adults

作　　者：钱海超[1] 王艳[1] 孙雪莲[1] QIAN Hai-chao;WANG Yan;SUN Xue-lian(Department of Emergency,Beijing Friendship Hospital,Capital Medicine University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院急诊科

出　　处：《临床和实验医学杂志》2019年第16期1766-1768,共3页Journal of Clinical and Experimental Medicine

基　　金：北京市医院管理局青年人才培养“青苗”计划(编号:QML20150104)

摘　　要：目的对青年和老年急性胰腺炎患者进行对比观察和危险因素分析。方法回顾性分析2013年1月至2018年12月首都医科大学附属北京友谊医院收治的130例青年急性胰腺炎患者(青年组)和156例老年急性胰腺炎患者(老年组)的病例资料,比较两组患者入院时的一般情况、体重指数、甘油三酯、C反应蛋白、随机血糖、住院时间、病情严重程度。分析急性胰腺炎发生的危险因素。结果青年组患者与老年组患者相比C反应蛋白(138.35±15.78 mg/L vs.97.23±19.89 mg/L)、甘油三酯(19.89±6.56 mmol/L vs.2.28±1.31 mmol/L)、随机血糖(9.01±3.19 mmol/L vs.6.15±1.21 mmol/L)、体重指数(30.12±5.21 kg/m^2vs.24.56±5.31 kg/m^2)均更高,差异具有统计学意义(P<0.05);青年组患者多伴有糖尿病,住院时间、并发症发生率及死亡率均高于老年组,差异具有统计学意义(P<0.05)。青年患者急性胰腺炎的危险因素包括高甘油三酯、随机血糖增高、高体重指数、饮酒;老年患者急性胰腺炎的危险因素包括高甘油三酯、胆囊结石。结论老年急性胰腺炎患者与青年急性胰腺炎患者危险因素不同,前者主要是胆囊结石,后者危险因素主要是高甘油三酯、随机血糖增高、高体重指数、饮酒。且青年急性胰腺炎病情较重,住院期间并发症发生率及病死率更高。Objective To comparative explore and analyze the risk factors of acute pancreatitis in young and old patients.Methods Retrospective analysis of 130 young patients with acute pancreatitis(youth group)and 156 elderly patients with acute pancreatitis(elderly group)admitted to this hospital during January 2013 to December 2018,the general condition of these patients at the time of admission,body mass index(BMI),blood levels of triglyceride,C-reactive protein,random blood glucose,hospitalization time,severity of the illness of patients in these 2 groups were compared.Results In comparison with the elderly group,patients in young group had higher blood levls of C-reactive protein(138.35±15.78 mg/L vs.97.23±19.89 mg/L),triglyceride(19.89±6.56 mmol/L vs.2.28±1.31 mmol/L),and randomized blood glucose(9.01±3.19 mmol/L vs.6.15±1.21 mmol/L),body mass index(30.12±5.21 kg/m^2 vs.24.56±5.31 kg/m^2),and the difference was statistically significant(P<0.05).Young patients were mostly accompanied by diabetes,and hospitalization time,complication rate,the mortality rate was higher than those of elderly group(P<0.05).The risk factors for acute pancreatitis in young patients include high level of triglycerides,high level of random blood glucose,high body mass index,high alcohol consumption,and risk factors for acute pancreatitis in old patients include high triglycerides and gallbladder stones.Conclusion Elderly patients with acute pancreatitis and young acute pancreatitis patients with different risk factors,the former is mainly gallstones,the latter risk factors are mainly high blood levels of triglycerides and random blood glucose,high body mass index and drinking.Young patients with acute pancreatitis are more severe,with higher complication rates and mortality during hospitalization.

关 键 词：急性胰腺炎 青年 老年 临床特点 危险因素 

分 类 号：R576[医药卫生—消化系统]