疏血通脉颗粒对卒中后认知功能障碍病人神经功能的影响  

Influences of Shuxue Tongmai Granule on Neural Function in the Treatment of Post-stroke Cognitive Impairment

作　　者：刘泰[1] 陈荣群[1] 何乾超[1] 张青萍[1] 谭璐璐[1] 陆银艳 LIU Tai;CHEN Rongqun;HE Qianchao;ZHANG Qingping;TAN Lulu;LU Yinyan(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学第一附属医院,南宁530023 [2]鹿寨县中医医院

出　　处：《中西医结合心脑血管病杂志》2019年第14期2092-2095,共4页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广西壮族自治区卫计委重点课题资助(No.S201410-01)

摘　　要：目的观察疏血通脉颗粒对卒中后认知功能障碍病人神经功能的影响。方法将166例卒中后认知功能障碍病人随机分为西药组与观察组,每组83例。西药组口服盐酸多奈哌齐片,观察组给予疏血通脉颗粒方。比较两组临床神经功能缺损程度(CSS)评分、简易智能量表(MMSE)评分及临床疗效。结果观察组的临床疗效较对照组明显改善(P<0.05)。干预1个月、3个月、6个月两组CSS评分、MMSE评分比较差异均有统计学意义(P<0.05)。结论疏血通脉颗粒可以促进卒中后认知功能障碍病人的神经功能恢复,改善病人认知功能。Objective To observe the effect of Shuxue Tongmai Granule on neural function in the treatment of post-stroke cognitive impairment.Methods one hundred and sixty-six patients were randomly divided into the observation group and the western medicine group,with eighty-three in each group.The western medicine group was given Donepezil.The observation group was given Shuxue Tongmai granule.The China stroke scale score,mini-mental state examination score,and clinical efficacy were compared between the two groups.Results The clinical efficacy in the treatment group was better than the control group(P<0.05).There was statistically significant difference in the scores of CSS and MMSE between the two groups at 1st,3rd,6th months after treament(P<0.05).Conclusion Shuxue Tongmai granule could promote the neural function,and cognitive function in patiens with cognitive impairment after stroke.

关 键 词：卒中 认知功能障碍 神经功能 疏血通脉颗粒 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R255.2[医药卫生—临床医学]