不同月龄人胎儿肝脏抗氧化能力初探  

Preliminary Study on Antioxidant Capacity of Human Fetal Liver of Different Months

作　　者：胡祥上 宫德正[2] 蒋建国 刘雨 蔡世昌 陈峡 于鹏辉 邹原[2] HU Xiang-shang;GONG De-zheng;JIANG Jian-guo;LIU Yu;CAI Shi-chang;CHEN Xia;YU Peng-hui;ZOU Yuan(Department of Medical College,Hunan University of Medicine,Hunan Huaihua 418000,China;Department of Physiology,Dalian Medical University,Liaoning Dalian 116027,China)

机构地区：[1]湖南医药学院医学院,湖南怀化418000 [2]大连医科大学生理教研室,辽宁大连116027

出　　处：《临床医药文献电子杂志》2019年第52期4-5,共2页Electronic Journal of Clinical Medical Literature

基　　金：湖南省教育厅科研项目(11C1010)老年人肝脏解偶联蛋白2表达与衰老关系的研究

摘　　要：目的探讨不同月龄胎儿肝脏组织中丙二醛(malondialdehyde,MDA)、谷胱甘肽(glutathione,GSH)和三磷酸腺苷(adenosine triphosphate,ATP)含量的变化趋势。方法选取临床4~10个月月龄的胎儿肝脏组织,分别测定MDA、GSH、和ATP的含量。结果 7月龄的胎儿肝脏组织中MDA含量最低、GSH含量最高、ATP含量最高。结论 7月龄的胎儿肝脏组织的代谢水平较高(较旺盛),抗氧化能力较强。Objective To investigate thevariation trends of malondialdehyde (MDA),glutathione (GSH) and adenosine triphosphate (ATP) levels in the liver of fetuses at different ages.Methods The liver tissues of fetuses aged 4 to 10 months were selected and the contents of MDA,GSH and ATP were determined. Results The contents of MDA were the lowest,and the contents ofGSH and ATP were the highest in the liver tissue of 7-month-old fetuses.Conclusion Fetal liver of 7 months has a higher metabolic level (more vigorous) and stronger antioxidant capacity.

关 键 词：活性氧 氧化应激 胎儿肝组织 

分 类 号：R963[医药卫生—微生物与生化药学]