低温等离子射频消融术治疗早期声门型喉癌32例的效果分析  

Effect of radiofrequency ablation of low temperature plasma knife in the treatment of 32 cases of early glottal carcinoma

作　　者：李剑峰[1] 陈火星 李欣[1] 李国栋[1] Li Jianfeng;Chen Huoxing;Li Xin;Li Guodong(Department of Otolaryngology, the People's Hospital of Shanxi Province, Taiyuan, Shanxi 030012, China)

机构地区：[1]山西省人民医院耳鼻咽喉科,太原030012

出　　处：《中国基层医药》2019年第15期1793-1797,共5页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨低温等离子射频消融术治疗早期声门型喉癌的效果及复发率。方法选取2012年2月至2016年1月山西省人民医院治疗的早期声门型喉癌患者64例为研究对象,依据治疗方案不同分为观察组与对照组各32例。观察组施行低温等离子射频消融术,对照组施行常规喉裂开术。记录两组手术相关指标、术后并发症,并对比两组术前、术后6个月语音变化情况(振幅微扰、基频微扰及谐噪比),随访两年,统计两组术后1年声带黏膜恢复情况及术后6个月、1年、2年复发率。结果观察组术中出血量较对照组少(P<0.05),手术用时及留院观察时间较对照组短(均P<0.05),术后并发症发生率[9.38%(3/32)]较对照组[31.25%(10/32)]低,术后1年声带黏膜光滑率[90.63%(29/32)]较对照组[62.50%(20/32)]高,差异均有统计学意义(χ^2=4.730、7.053,均P<0.05)。两组术前振幅微扰、基频微扰及谐噪比差异均无统计学意义(均P>0.05);观察组术后振幅微扰、基频微扰较对照组低,谐噪比较对照组高,差异均有统计学意义(t=18.618、4.258、2.579,均P<0.05);观察组术后6个月、1年、2年复发率均较对照组低(χ^2=4.598、6.335、4.730,均P<0.05)。结论对早期声门型喉癌患者施行低温等离子射频消融术,可明显减少术中出血量,有效缩短手术用时及术后留院观察时间,显著降低术后并发症发生率及复发率,且可改善患者语音情况,促进声带黏膜恢复光滑。Objective To investigate the effect and recurrence rate of radiofrequency ablation of low temperature plasma knife in the treatment of patients with early glottal carcinoma. Methods A total of 64 cases of early glottic carcinoma in the People's Hospital of Shanxi Province from February 2012 to January 2016 were divided into observation group and control group according to the different treatment schemes, with 32 cases in each group.The observation group was treated with radiofrequency ablation of low temperature plasma knife, and the control group was performed with routine larynx cleft surgery.The surgical related indicators and postoperative complications of the two groups were recorded.The phonetic changes (amplitude perturbation, fundamental frequency perturbation and harmonic noise ratio) before and 6 months after operation of two groups were compared.After 2 years of follow-up, the recovery of vocal mucosa in the two groups after 1 year of operation and the recurrence rate of 6 months, 1 year and 2 years after operation of the two groups were statistically recorded. Results The intraoperative blood loss in the observation group was less than that in the control group(P<0.05), and the operative time and hospital stay observation time in the observation group were shorter than those in the control group(all P<0.05). The incidence rate of postoperative complications in the observation group [9.38%(3/32)] was lower than that in the control group[31.25%(10/32)], and the smoothness rate of the vocal cords at 1 year after operation in the observation group [90.63%(29/32)] was higher than that in the control group[62.50%(20/32)], the difference were statistically significant(χ^2=4.730, 7.053, all P<0.05). There were no statistically significant differences in amplitude perturbation, fundamental frequency perturbation and harmonic noise ratio between the two groups(all P>0.05). After operation, the amplitude perturbation and the fundamental frequency perturbation in the observation group were lower than those of th

关 键 词：喉肿瘤 声门 消融技术 冷冻外科手术 喉裂开术 疗效比较研究 

分 类 号：R739.65[医药卫生—肿瘤]