前列腺癌诊断标志物检测研究进展  

Progress in the detection of diagnostic markers for prostate cancer

作　　者：李丽[1] 宋茜 刘冉录[1] LI Li;SONG Qian;LIU Ran-lu(Department of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China)

机构地区：[1]天津医科大学第二医院泌尿外科天津市泌尿外科研究所

出　　处：《天津医药》2019年第8期880-884,共5页Tianjin Medical Journal

基　　金：天津市应用基础及前沿技术研究计划重点项目（15JCZDJC35900）;天津市教委项目（20140122)

摘　　要：近年来,我国前列腺癌(PCa)的发病率呈显著增高的态势。同时,相较于发达国家,我国PCa患者的死亡率较高。在过去10年中,用于PCa诊断的生物标志物的相关研究取得了较大进展,这些标志物检测证据基础也在迅速发展。本文对PCa生物标志物检测领域的最新研究进展加以综述,以期为临床医务人员更好地进行决策提供借鉴。In recent years, the incidence of prostate cancer in China has increased significantly. At the same time, compared with developed countries, the mortality rate of prostate cancer in China is higher. In the past decade, the relevant research on biomarkers for the diagnosis of prostate cancer has made great progress, and the evidence base for the detection of these markers is also rapidly developing. We reviewed a large number of literatures and reviewed the latest developments in the field of prostate cancer biomarker testing in order to provide a reference for clinical medical staff to make better decisions.

关 键 词：前列腺肿瘤 前列腺特异抗原 生物标记 肿瘤 外泌体 前列腺抗原3 前列腺健康指数 

分 类 号：R737.25[医药卫生—肿瘤]