比较不同方案对幽门螺杆菌感染的治疗效果  

Comparison of Different Methods for the Efficacy of Helicobacter Pylori Infection

作　　者：章宏伟[1] 钱江[1] ZHANG Hongwei;QIAN Jiang(The Third Affiliated Hospital of Gannan Medical College,Ganzhou 341000,China)

机构地区：[1]赣南医学院第三附属医院

出　　处：《中国医学创新》2019年第20期138-141,共4页Medical Innovation of China

摘　　要：目的:研究不同方案对幽门螺杆菌感染的治疗效果。方法:选取2016年6月-2018年6月本院收治的幽门螺杆菌感染患者70例,按随机数字表法分为试验组(n=35)与对照组(n=35),试验组采用雷贝拉唑+枸橼酸铋钾胶囊+阿莫西林+呋喃唑酮治疗,对照组采用兰索拉唑+克拉霉素+奥硝唑治疗。比较两组幽门螺杆菌根除率、不良反应发生率、肝功能(ALT、AST)水平、治疗费用、治疗依从性、生活质量与炎症因子水平。结果:试验组幽门螺杆菌根除率(94.29%)高于对照组(74.29%),试验组不良反应发生率(14.29%)低于对照组(37.14%),差异均有统计学意义(P<0.05)。治疗后,试验组ALT、AST与治疗费用均低于对照组(P<0.05)。试验组治疗依从性(97.14%)高于对照组(80.00%),差异有统计学意义(P<0.05)。试验组各项生活质量评分均高于对照组(P<0.05)。试验组各炎症因子水平均低于对照组(P<0.05)。结论:雷贝拉唑+枸橼酸铋钾胶囊+阿莫西林+呋喃唑酮治疗幽门螺杆菌感染患者效果显著,可以明显提高幽门螺杆菌感染根除率,提高患者生活质量,值得临床推广借鉴。Objective:To study the efficacy of different methods for the Helicobacter pylori infection.Method:70 patients with helicobacter pylori infection admitted to our hospital from June 2016 to June 2018 were selected and divided into experimental group(n=35)and control group(n=35)according to random number table method.The experimental group was treated with Rabeprazole+Bismuth Potassium Citrate Capsule+Amoxicillin+Furazolidone,the control group was treated with Lansoprazole+Clarithromycin+Ornidazole.The eradication rate of Helicobacter pylori,incidence of adverse reactions,liver function(ALT,AST),treatment costs,treatment compliance,quality of life,inflammatory factors in two groups were compared.Result:The eradication rate of Helicobacter pylori infection in the experimental group(94.29%)was higher than that in the control group(74.29%),the incidence rate in the experimental group(14.29%)was lower than that in the control group(37.14%),the differences were statistically significant(P<0.05).After treatment,ALT,AST and treatment costs in the experimental group were lower than those in the control group(P<0.05).The treatment compliance in the experimental group(97.14%)was higher than that in the control group(80.00%),the difference was statistically significant(P<0.05).The each quality of life scores in the experimental group were higher than those of the control group(P<0.05).The each inflammatory factor levels in the experimental group were lower than those in the control group(P<0.05).Conclusion:Rabeprazole+Bismuth Potassium Citrate Capsu le+Amoxicillin+Furazolidone is effective in the treatment of Helicobacter pylori infection.It can significantly improve the eradication rate of Helicobacter pylori and the quality of life of patients.It is worthy of clinical promotion.

关 键 词：不同方案 幽门螺杆菌感染 根除率 治疗效果 治疗费用 治疗依从性 

分 类 号：R573[医药卫生—消化系统]