口腔卫生与非吸烟非饮酒女性口腔癌关系研究  

Relationship of oral hygiene with oral cancer in non-smoking and non-drinking women

作　　者：韦存志 温庆春[1] 陈雷[1] 毛晓斌 WEI Cun-zhi;WEN Qing-chun;CHEN Lei;MAO Xiao-bin(The First People’s Hospital of Yibin City,Yibin,Sichuan 644000,China)

机构地区：[1]宜宾市第一人民医院

出　　处：《实用预防医学》2019年第8期955-958,共4页Practical Preventive Medicine

摘　　要：目的研究口腔卫生状况与非吸烟非饮酒女性口腔癌的关系。方法收集2012年10月-2017年9月我院口腔颌面外科经术后病理确诊的非吸烟非饮酒女性口腔癌患者162例,同期选取在该院体检的214位非吸烟非饮酒健康女性作为对照组。口腔卫生考察指标包括刷牙频率、牙齿缺失数、口腔不良修复体、规律性看牙医、复发性口腔溃疡。应用多因素logistic回归模型分析口腔卫生评分与非吸烟非饮酒女性口腔癌的关联。结果刷牙频率<2次/d、牙齿缺失≥5颗、有口腔不良修复体、无规律性看牙医、有复发性口腔溃疡是非吸烟非饮酒女性口腔癌的危险因素(均P<0.05),OR(95%CI)值分别为1.49(1.09~2.08)、1.80(1.16~2.84)、1.51(1.04~2.23)、1.74(1.16~2.57)、7.29(3.98~13.35)。多因素logistic回归模型分析结果显示,口腔卫生评分与非吸烟非饮酒女性口腔癌发生存在关联,分值越大,危险程度就越高(χ^2=24.179,P<0.001)。结论口腔卫生状况与非吸烟非饮酒女性口腔癌发生具有一定的关系。Objective To study the association between oral hygiene status and oral cancer among non-smoking and non-drinking women. Methods We recruited 162 non-smoking and non-drinking female patients who were postoperatively pathologically confirmed as oral cancer in Department of Oral and Maxillofacial Surgery, the First People’s Hospital of Yibin City from October 2012 to September 2017. And 214 non-smoking and non-drinking healthy women were simultaneously selected from health examination center in the same hospital to serve as the control group. Oral hygiene related variables included the frequency of teeth brushing, number of teeth loss, poor prosthesis, regular dental visits and recurrent oral ulceration. Multivariate logistic regression model was used to analyze the association between the score of oral hygiene and the incidence of oral cancer in non-smoking and non-drinking female patients. Results Daily teeth brushing less than twice(OR=1.49, 95%CI:1.09-2.08), teeth loss more than or equal to 5(OR=1.80, 95%CI:1.16-2.84), having poor prosthesis(OR=1.51, 95%CI:1.04-2.23), irregular dental visits(OR=1.74, 95%CI:1.16-2.57) and suffering recurrent oral ulceration(OR=7.29, 95%CI:3.98-13.35) were risk factors for oral cancer in non-smoking and non-drinking women(all P<0.05). Multivariate logistic regression analysis showed that the score of oral hygiene was associated with the occurrence of oral cancer in non-smoking and non-drinking female patients. The higher the score, the higher the risk(χ^2=24.179, P<0.001). Conclusions There is a relationship between the status of oral hygiene and the occurrence of oral cancer in non-smoking and non-drinking women.

关 键 词：口腔卫生 口腔癌 女性 非吸烟 口腔溃疡 

分 类 号：R780.1[医药卫生—口腔医学]