高眼压状态下角膜内皮的损伤与修复  

Corneal Wound Healing in High Intraocular Pressure

作　　者：曲勃[1] 刘丹霞 张旺 QU Bo;LIU Danxia;ZHANG Wang(Department of Ophthalmology,The Fourth Affiliated Hospital,The Eye Hospital,China Medical University,Lens Science Research Key Laboratory of Liaoning Province,Shenyang 110005,China)

机构地区：[1]中国医科大学附属第四医院眼科中国医科大学眼科医院辽宁省晶状体学重点实验室

出　　处：《中国医科大学学报》2019年第8期752-755,共4页Journal of China Medical University

基　　金：辽宁省自然科学基金（2014021005）

摘　　要：角膜内皮细胞的功能对维持角膜透明起着至关重要的作用。高眼压损伤角膜内皮细胞,引起角膜内皮细胞数目减少,从而导致角膜通透性下降。角膜内皮在体内无法进行增殖,但在特定条件下具有增殖能力。角膜内皮细胞在高压力状态下受损后,依靠受损区周边角膜内皮细胞扩大及移行修复。本文对高眼压损伤角膜内皮及角膜内皮受损后的修复进行了综述。Normal physiological function of corneal endothelial cells is important to the transparency of the cornea. High intraocular pressure could damage the corneal endothelial cells with reducing the density of corneal endothelial cells,and lead to corneal edema.Endothelial cells can not regenerate in vivo,only rely on neighboring cells migration and expansion when injured by high intraocular pressure. This review tried to introduce the corneal wound healing in high intraocular pressure.

关 键 词：角膜内皮 高眼压 损伤 修复 

分 类 号：R772.2[医药卫生—眼科]