Solitaire支架动脉取栓术联合多模式血管再通术治疗急性脑梗死的效果分析  

Effect analysis of Solitaire stent mechanical thrombolysis combined with multimode vascular reoperation in the treatment of acute cerebral infarction

作　　者：李小勇 林建美 LI Xiaoyong;LIN Jianmei(Department of Neurology,Ziyang First People′s Hospital,Sichuan Province,Ziyang 641300,China;Department of Nephrology,Ziyang First People′s Hospital,Sichuan Province,Ziyang 641300,China)

机构地区：[1]四川省资阳市第一人民医院神经内科,四川资阳641300 [2]四川省资阳市第一人民医院肾病内科,四川资阳641300

出　　处：《中国医药导报》2019年第22期158-161,共4页China Medical Herald

摘　　要：目的探讨Solitaire支架动脉取栓术联合多模式血管再通术治疗急性脑梗死的效果。方法分析四川省资阳市第一人民医院2012年1月~2018年10月收治的99例急性脑梗死患者的临床资料,根据治疗方法不同进行分组,对照组(49例)和观察组(50例)。对照组采用Solitaire支架动脉取栓术进行治疗,观察组在对照组的基础上联合动脉溶栓术、球囊扩张术、支架置入术等多个模式的血管再通术进行治疗。观察两组患者发病-置鞘成功时间、发病-血管再通时间;观察两组患者干预前后美国国立卫生研究院卒中量表(NIHSS)评分和改良Rankin评分量表(mRS)评分;观察两组患者血管再通率和临床治疗总有效率。结果两组患者发病-置鞘成功时间、发病-血管再通时间、干预前NIHSS评分和mRS评分比较,差异均无统计学意义(P>0.05);干预后,两组患者的NIHSS评分和mRS评分均低于干预前,且观察组低于对照组,差异均有统计学意义(P<0.05);两组患者血管再通率、临床治疗总有效率比较,差异有统计学意义(P<0.05)。结论Solitaire支架动脉取栓术联合多模式血管再通术治疗急性脑梗死患者,改善了神经功能,提高了血管再通和疗效,值得临床推广应用。Objective To approach effect of Solitaire stent mechanical thrombolysis combined with multimode vascular reoperation in the treatment acute cerebral infarction.Methods Clinical data of 99 patients with acute cerebral infarction in Neurology Department of Ziyang First People′s Hospital of Sichuan Province from January 2012 to October 2018 were analyzed,and they were grouped by different treatment methods,control group (49 cases) and detection group (50 cases).The control group was treated with Solitaire stent mechanical thrombolysis,while the observation group was treated with multimode vascular reoperation,including combined arterial embolization,balloon dilation and stent implantation etc,on the basis of the control group.The disease-successfully scabbed time,disease-vascular bypass time of patients in the two groups were observed;the National Institutes of health stroke scale (NIHSS) score and modified Rankin scale (mRS) score of patients in the two groups before and after intervention were observed;vascular bypass rate and clinical treatment total efficiency rate of patients in the two groups were observed.Results There were no statistically significant difference in disease-successfully scabbed time,disease-vascular bypass time,and NIHSS and mRS scores between two groups before intervention (P > 0.05).After intervention,the NIHSS score and mRS score of two groups were lower than before intervention,and those of the detection group were lower than the control group,the differences were statistical significance (P < 0.05).The vascular bypass rate and clinical treatment total efficiency rate were compared between two groups,the differences were statistical significance (P < 0.05).Conclusion Solitaire stent mechanical thrombolysis combined with multimode vascular reoperation in the treatment of acute cerebral infarction can improve the nerve function,increase vascular bypass and curative effect,it is worthy of clinical promotion and application.

关 键 词：Solitaire支架动脉取栓术 多模式血管再通术 急性脑梗死 美国国立卫生研究院卒中量表 改良Rankin评分量表 

分 类 号：R783.1[医药卫生—口腔医学]