非酒精性脂肪性肝病与代谢综合征的中西医相关性研究进展  

Research Progress of Correlation between Nonalcoholic Fatty Liver Disease and Metabolic Syndrome in Traditional Chinese Medicine and Western Medicine

作　　者：段绍杰 陈佳良[1] 陈洁[1] 肖琨珉 贾子君 姚树坤[2] DUAN Shaojie;CHEN Jialiang;CHEN Jie;XIAO Kunmin;JIA Zijun;YAO Shukun(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Gastroenterology,China-Japan Friendship Hospital,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院消化内科,北京100029

出　　处：《医学综述》2019年第15期2935-2939,共5页Medical Recapitulate

基　　金：国家科技支撑计划课题(2014BAI08B02);北京市科技计划课题(Z171100001717008);中央高校基本科研业务费专项资金;中日友好医院生物医学转化工程系列研究项目(PYBZ1815)

摘　　要：随着人们饮食结构及生活方式的改变,非酒精性脂肪性肝病(NAFLD)和代谢综合征(MS)的发病率迅速升高,且有着密切联系,严重危害国民健康。两者均以胰岛素抵抗为关键病机,以中心性肥胖为重要始发因素,且受饮食、心理、生活方式、肠道菌群以及年龄、性别、遗传等多种因素的影响。同时,两者在中医病因病机及体质类型和证候特点上也具有高度一致性。未来,应从中西医结合的角度探讨NAFLD和MS的相关性,以更加系统全面地认识两者之间的联系。With the changes in people′s dietary structure and lifestyle,the incidences of nonalcoholic fatty liver disease(NAFLD)and metabolic syndrome(MS)have risen rapidly,which are closely linked,seriously jeopardizing people′s health.Insulin resistance is the key pathogenesis,central obesity is an important initiating factor,and diet,psychology,lifestyle,intestinal flora,age,gender,genetics are all influecing factors for both diseases.At the same time,they also have a high degree of consistency in the etiology and pathogenesis in traditional Chinese medicine system,as well as the constitutional types and correlative syndromes.In the future,we should discuss the correlation between NAFLD and MS from the perspective of integrated traditional Chinese and western medicine,in order to understand the relationship between them more systematically and comprehensively.

关 键 词：非酒精性脂肪性肝病 代谢综合征 中心性肥胖 胰岛素抵抗 中西医结合 

分 类 号：R575.5[医药卫生—消化系统] R589[医药卫生—内科学]