沈阳地区幽门螺杆菌感染现状调查分析  

Investigation on infection status of population with Helicobacter pylori infection in Shengyang region

作　　者：郭颖[1] 裴冬梅[1] 张耐思 GUO Ying;PEI Dongmei;ZHANG Naisi(Department of General Medicine,Shengjing Hospital Affiliated to China Medical University,Shenyang,Liaoning,110004)

机构地区：[1]中国医科大学附属盛京医院全科医学科

出　　处：《实用临床医药杂志》2019年第13期99-101,105,共4页Journal of Clinical Medicine in Practice

基　　金：中国医科大学“十三五”医学教育科学研究课题(YDJK2016008)

摘　　要：目的 了解沈阳地区人群幽门螺杆菌(Hp)感染现状,并分析其感染特点及其相关因素。方法 收集2018年1—12月于本院体检中心检测Hp的人群相关资料。根据年龄将患者分为3组,青年组(17~29岁)、中年组(30~59岁)和老年组(≥60岁);根据感染情况分为阳性组和阴性组。分析不同性别、不同年龄段感染的特点及Hp感染与血糖、血脂间的相关性。结果 11775例患者进行了14C尿素呼气试验检测,总感染率为30.99%。阳性组中男性共2376例,感染率为65.11%;女性共1273例,感染率为34.89%,差异有统计学意义(P<0.05)。青年组的Hp阳性和阴性率与中年组、老年组比较,差异有统计学意义(P<0.01),而中年组和老年组比较,差异无统计学意义(P>0.05);Hp阳性组的血糖、甘油三酯及低密度胆固醇水平均高于Hp阴性组,差异有统计学意义(P<0.05),而2组总胆固醇和高密度胆固醇差异无统计学意义(P>0.05)。结论 Hp阳性感染与年龄、性别、血糖、甘油三酯及低密度胆固醇有关,与总胆固醇和高密度胆固醇无显著相关性。Objective To investigate the infection status of Helicobacter pylori(Hp)infection in Shenyang region,and to analyze its infection characteristics and related factors.Methods The data of population with Hp infection detected in our physical examination center from January to December 2018 were retrospectively studied.These patients were divided into three groups according to varied ages:the youth group,the middle-aged group and the elderly group,and two groups according to the infection conditions:Hp-positive group and negative group.The characteristics of infections in varied gender and age groups were analyzed,and relationship between Hp infection and blood glucose,blood lipids were observed.Results 14 C urea exhalation test was carried out in 11 775 people,with total infection rate of 30.99%.In the positive group,there were 2 376 male cases,and 1 273 female cases,with the infection rate of 65.11%,34.89%,respectively,the differences were statistically significant(P<0.05).The positive and negative rates of Hp in the young group showed significant differences compared to those in the middle-aged and elderly groups(P<0.01),but no significant differences were seen between the middle-aged group and the elderly group(P>0.05).The blood glucose,triglyceride and low-density cholesterol levels in Hp-positive group were higher than those in Hp-negative group(P<0.05),but there was no significant between-group differences in total cholesterol and high-density cholesterol(P>0.05).Conclusion Hp positive infection is related to age,sex,blood glucose,triglyceride and low-density cholesterol,but has no significant correlation with total cholesterol and high-density cholesterol.

关 键 词：幽门螺杆菌 血糖 血脂 总胆固醇 高密度胆固醇 

分 类 号：R573[医药卫生—消化系统]