一种便携式稳态视觉诱发脑电信号采集系统设计  

Design of a portable SSVEP signal acquisition system

作　　者：董亚斌 王磊[1] 王琳琳 李倩 柴林燕[2] 王妍[1] Dong Yabin;Wang Lei;Wang Linlin;Li Qian;Chai Linyan;Wang Yan(Institute of Biomedical Engineering,Chinese Academy of Medical Sciences & Peking Union Medical College,Tianjin 300192,China;Department of Oncological Radiotherapy,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]中国医学科学院北京协和医学院生物医学工程研究所,天津300192 [2]西安交通大学第一附属医院肿瘤放疗科,710061

出　　处：《国际生物医学工程杂志》2019年第3期222-226,共5页International Journal of Biomedical Engineering

基　　金：中国医学科学院医学与健康科技创新工程项目(2018-I2M-AI-012);天津市自然科学基金(16JCYBJC28900).

摘　　要：目的设计一种便携式脑电采集设备,用于稳态视觉诱发电位(SSVEP)信号的采集与分析.方法采用微处理器MSP432P401系列单片机控制高性能集成模拟前端ADS1299,实现脑电信号(EEG)的采集、放大和模数(AD)转换.通过WIFI将数字EEG信号发送到上位机进行处理.采集分析3名受试者的自发脑电信号和稳态视觉诱发脑电信号对系统性能进行验证.结果采集到的受试者闭眼自发脑电信号α波节律明显.功率谱密度图显示,在对应刺激频率下,稳态视觉诱发脑电信号频率和谐波频率处均呈现峰值,表明系统工作正常,性能良好.结论设计的便携式脑电采集系统能准确采集到人体自发和诱发脑电信号,为SSVEP技术的临床应用提供了技术保障.Objective To design a portable electroencephalography(EEG) acquisition system to acquire and analysis steady-state visual potentials (SSVEP).Methods The microprocessor MSP432P401 series MCU was used to control the high-performance integrated analog front end ADS1299 to realize the acquisition,amplification and analog-to-digital (AD) conversion of EEG signals.The digital EEG signal is sent to the host computer for processing by WIFI.Spontaneous EEG signals and steady-state visually evoked EEG signals from 3 healthy subjects were collected to verify system performance.Results The collected signal had a clear α-wave rhythm of closed-eye spontaneous EEG signals.The power spectrum density shows that the steady-state visually induced EEG signal frequency and harmonic frequency peak at the corresponding stimulation frequency,indicating that the system works normally and the performance is good.Conclusions The designed portable EEG acquisition system can accurately collect the spontaneous and induced EEG signals of the human body,which provides technical support for the clinical application of SSVEP technology.

关 键 词：脑电采集 稳态视觉诱发 ADS1299 WIFI 

分 类 号：R741.044[医药卫生—神经病学与精神病学] TN911.7[医药卫生—临床医学]