4181例牙源性肿瘤及囊肿临床病理分析  

Odontogenic tumors and odontogenic cysts:a clinical and pathological analysis of 4 181 cases

作　　者：苏屹坤 王婧[1] 张桐菲[2] 张泽兵[1] Su Yikun;Wang Jing;Zhang Tongfei;Zhang Zebing(Department of Pathology,School and Hospital of Stomatology,Jilin University,Changchun 130021,China;Department of Medical Administration,School and Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医学院病理科,长春130021 [2]吉林大学口腔医学院医务部,长春130021

出　　处：《中华口腔医学杂志》2019年第8期546-552,共7页Chinese Journal of Stomatology

基　　金：吉林省科技发展计划(20190701071GH).

摘　　要：目的探讨牙源性肿瘤及牙源性囊肿的发病情况与构成比特点,为临床治疗提供参考。方法按照WHO 2017年的组织学分类标准,收集1961年1月至2017年12月在吉林大学口腔医学院病理科确诊为牙源性肿瘤或牙源性囊肿的4 181例患者的病理资料。统计分析各类肿瘤及囊肿的病理类型、性别、就诊年龄及部位等构成特点。结果4 181例病例中牙源性肿瘤1 055例,牙源性囊肿3 126例。牙源性肿瘤中,良性肿瘤占96.11%(1 014/1 055),恶性肿瘤占3.89%(41/1 055)。牙源性肿瘤最常见的病理类型为成釉细胞瘤[53.27%(562/1 055)]、牙骨质骨化纤维瘤[21.23%(224/1 055)]及牙瘤[12.99%(137/1 055)],男女比为1∶1.04,高发年龄为10~39岁,上下颌比为1∶2.85。牙源性囊肿最常见的病理类型为根尖周囊肿[50.45%(1 577/3 126)]、牙源性角化囊肿[25.59%(800/3 126)]及含牙囊肿[21.56%(674/3 126)],男女比为1.37∶1,高发年龄为20~49岁,上下颌比为1.37∶1。结论在新分类标准下,57年间吉林地区牙源性肿瘤的发生无性别偏好,好发于下颌,成釉细胞瘤是最常见的牙源性肿瘤;牙源性囊肿男性发生率高于女性,好发于上颌,根尖周囊肿是最常见的牙源性囊肿类型。Objective To investigate the incidence and constituent ratio of odontogenic tumors or odontogenic cysts in School and Hospital of Stomatology,Jilin University and to provide the reference for the clinical treatment.Methods According to the WHO 2017 histological classification criteria,the pathological data of 4181 patients diagnosed as odontogenic tumors or odontogenic cysts in the Department of Pathology,Jilin University Stomatological Hospital from January 1961 to December 2017 were collected.Statistical analysis of the pathological types,gender,age and location of various tumors and cysts was conducted.Results Of 4 181 cases,1 055 were tumors and 3 126 were cysts.Among odontogenic tumors,benign tumors accounted for 96.11%(1 014/1 055),and malignant tumors accounted for 3.89%(41/1 055).The most common pathological type of odontogenic tumors was ameloblastoma [53.27%(562/1 055)],followed by cemento-ossifying fibroma [21.23%(224/1 055)] and odontoma [12.99%(137/1 055)].The male-female ratio was 1∶1.04.The high-risk ages were 10-39.Maxilla-mandible ratio was 1∶2.85.As for cysts,radicular cysts [50.45%(1 577/3 126)] was the most common pathological type,followed by odontogenic keratocyst [25.59%(800/3 126)] and dentigerous cysts [21.56%(674/3 126)].The male-female ratio was 1.37∶1.The high-risk ages were 20-49.Maxilla-mandible ratio was 1.37∶1.Conclusions There was no gender preference for odontogenic tumors in Jilin Province area in the 57 years.The majority tumors occurred in the radicular.The most common pathological type was ameloblastoma.As for odontogenic cysts,males showed a higher incidence and the majority cysts occurred in the maxilla.The most common pathological type was radicular cysts.

关 键 词：牙源性肿瘤 牙源性囊肿 回顾性研究 

分 类 号：R739.8[医药卫生—肿瘤]