细胞减灭术联合腹腔热灌注化疗用于结直肠癌腹膜转移的治疗进展  

Research progress in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy for peritoneal metastasis of colorectal cancer

作　　者：傅志聪 刘剑文 樊敬文 Fu Zhicong;Liu Jianwen;Fan Jingwen(Department of Gastrointestinal Surgery,the University of Hong Kong-Shenzhen Hospital,Shenzhen 518000,China;Department of Colorectal Surgery,the University of Hong Kong-Queen Mary Hospital,Hongkong 999077,China)

机构地区：[1]香港大学深圳医院胃肠外科,518000 [2]香港大学玛丽医院结直肠外科,999077

出　　处：《中华消化外科杂志》2019年第8期747-752,共6页Chinese Journal of Digestive Surgery

摘　　要：结直肠癌腹膜转移传统上被认为是肿瘤终末期表现之一。近年来,细胞减灭术联合腹腔热灌注化疗在延长患者生存时间和延缓肿瘤复发等方面取得较大进展。国内外结直肠癌治疗指南将细胞减灭术联合腹腔热灌注化疗作为腹膜转移的有效治疗方式。本文对其治疗方式进行概述,并结合结直肠癌腹膜转移治疗领域研究进展和笔者临床经验,展望未来发展方向。Colorectal cancer peritoneal metastasis has traditionally been considered as one of the end-stage manifestations. Recently, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy achieved promising results in prolonging survival of patients and reducing tumor recurrences. Many guidelines suggested that the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is an acceptable treatment for peritoneal metastasis. This article highlighted the treatment method, reviewed the latest evidence in treatment of colorectal cancer peritoneal metastasis and explored future direction.

关 键 词：结直肠肿瘤 结直肠癌 腹膜转移 腹腔热灌注化疗 细胞减灭术 

分 类 号：R735.34[医药卫生—肿瘤]