Advances in capillary electro-chromatography  

作　　者：Zhenkun Mao Zilin Chen 

机构地区：[1]Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China [2]State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Beijing 10080, China

出　　处：《Journal of Pharmaceutical Analysis》2019年第4期227-237,共11页药物分析学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.81872828 and 81573384)

摘　　要：Capillary electrochromatography (CEC) is a micro-scale separation technique which is a hybrid between capillary electrophoresis (CE) and liquid chromatography (LC). CEC can be performed in packed, monolithic and open-tubular columns. In recent three years (from 2016 to 2018), enormous attention for CEC has been the development of novel stationary phases. This review mainly covers the development of novel stationary phases for open-tubular and monolithic columns. In particular, some biomaterials attracted increasing interest. There are no significant breakthroughs in technology and principles in CEC. The typical CEC applications, especially chiral separations are described.Capillary electrochromatography(CEC)is a micro-scale separation technique which is a hybrid between capillary electrophoresis(CE)and liquid chromatography(LC).CEC can be performed in packed,monolithic and open-tubular columns.In recent three years(from 2016 to 2018),enormous attention for CEC has been the development of novel stationary phases.This review mainly covers the development of novel stationary phases for open-tubular and monolithic columns.In particular,some biomaterials attracted increasing interest.There are no significant breakthroughs in technology and principles in CEC.The typical CEC applications,especially chiral separations are described.

关 键 词：CAPILLARY ELECTROCHROMATOGRAPHY OPEN-TUBULAR COLUMN Monolithic COLUMN Novel stationary PHASES Separation modes 

分 类 号：R[医药卫生]