卵巢微囊性间质肿瘤1例  

Ovarian microcystic stromal tumor: A case report

作　　者：李佳美 陈敏[1] 李奕锋[1] 孙平丽[1] LI Jiamei;CHEN Min;LI Yifeng;SUN Pingli(Department of Pathology,The Second Hospital of Jilin Universitty,Changchun 130022,China)

机构地区：[1]吉林大学第二医院病理科

出　　处：《临床与病理杂志》2019年第8期1847-1852,共6页Journal of Clinical and Pathological Research

基　　金：吉林省科技发展计划项目吉林省重点实验(20170622006JC);吉林省财政厅项目(3D5177723429)~~

摘　　要：对1例卵巢微囊性间质肿瘤(microcystic stromal tumor,MCST)患者进行临床、病理回顾性分析。患者,女,65岁,检查发现右侧卵巢肿物,肿物直径约12cm,包膜光滑完整,切面呈囊实性。镜下肿瘤主要由微囊区、实性细胞丰富区及胶原纤维间质构成。免疫表型:β-catenin,Vimentin,WT1,CD10弥漫阳性,ER,PR,α-inhibin,calretinin,EMA均为阴性,Ki-67小于1%。A clinical and pathological retrospective analysis was performed on a patient with microcystic stromal tumour (MCST),and the relevant literature was reviewed.A 65-year-old femal,who was found to have a right ovarian mass and the tumor was about 12 cm,with smooth envelope and solid-cystic cut surface.Microscopically, microcysts,solid area and hyaline degenerated fibrous stroma were variably mixed.Immunophenotype:tumor cells were diffusely and strongly positive for β-catenin,Vimentin,WT1,CD10,however,ER,PR,α-inhibin, calretinin,EMA were mostly negative,Ki67 labeling index was less than 1%.MCST is a relatively rare disease.

关 键 词：卵巢微囊性间质肿瘤 Β-连环蛋白 CTNNB1基因突变 

分 类 号：R737.31[医药卫生—肿瘤]