氧疗联合三乙醇胺、芦荟防治急性放射性皮炎的疗效观察  

Observation on efficacy of oxygen therapy combined with triethanolamine and Aloe on the prevention and treatment of acute radiation dermatitis

作　　者：和劲光[1] 陈玉茹 HE Jin-guang(Heze Municipal Hospital,Heze 274000,China)

机构地区：[1]菏泽市立医院,274000 [2]不详

出　　处：《中国实用医药》2019年第24期14-16,共3页China Practical Medicine

摘　　要：目的观察氧疗联合三乙醇胺、芦荟防治急性放射性皮炎的临床疗效。方法150例颈胸部恶性肿瘤初次放疗患者作为研究对象,放射靶区包括原发灶及淋巴结引流区。随机分成治疗组和对照组,各75例。对照组给予三乙醇胺、芦荟凝胶膏外涂,治疗组在对照组基础上同时用氧疗。治疗期间常规皮肤护理,观察对比两组急性放射性皮炎发生情况及不同皮肤损伤面积患者感染情况,对比两组愈合时间、治疗疗效及生活质量改善情况。结果治疗组患者急性放射性皮炎发生情况优于对照组,差异具有统计学意义(P<0.05)。两组皮肤损伤直径<1cm的患者均未感染。治疗组皮肤损伤直径≥1cm的患者感染率0低于对照组的1.33%,但差异无统计学意义(P>0.05)。治疗组愈合时间优于对照组,差异具有统计学意义(U=5.533,P<0.05)。治疗组中位愈合时间短于对照组,差异具有统计学意义(P<0.05)。治疗组治疗总有效率98.7%高于对照组的80.0%,差异具有统计学意义(P<0.05)。治疗组生活质量改善有效率98.7%高于对照组的78.7%,差异有统计学意义(P<0.05)。结论氧疗联合三乙醇胺、芦荟能有效防治患者放疗中的急性放射性皮炎,使用方便,安全可靠,不良反应轻,可明显减轻患者痛苦,提高患者生活质量,临床上值得推广。Objective To observe the clinical efficacy of oxygen therapy combined with triethanolamine and aloe on the prevention and treatment of acute radiation dermatitis.Methods A total of 150 patients with cervical and thoracic malignant tumors undergoing primary radiotherapy as study subjects,and their target areas included primary focus and lymph node drainage area.They were randomly divided into treatment group and control group,with 75 cases in each group.The control group received external application of triethanolamine and Aloe gel paste,and the treatment group received oxygen therapy on the basis of the control group.Both groups received conventional skin nursing during treatment.The occurrence of acute radiation dermatitis and infection in patients with different skin lesion areas between the two groups was observed and compared.The healing time, treatment efficacy and improvement of quality of life between the two groups was compared.Results The treatment group had better occurrence of acute radiation dermatitis than that of the control group,and the difference was statistically significant (P<0.05).No infection occurred in patients with skin lesion diameter <1 cm in both groups. The treatment group had lower infection rate in patients with skin lesion diameter ≥1 cm as 0 than 1.33% in the control group,and the difference was not statistically significant (P>0.05).The treatment group had better healing time than that of the control group,and the difference was statistically significant (U=5.533,P<0.05).The treatment group had shorter median healing time than that of the control group,and the difference was statistically significant (P<0.05).The treatment group had higher total effective rate of treatment as 98.7% than 80.0% in the control group,and the difference was statistically significant (P<0.05).The treatment group had higher effective rate of improvement of quality of life as 98.7% than 78.7% in the control group,and the difference was statistically significant (P<0.05).Conclusion Oxygen therapy combin

关 键 词：急性放射性皮炎 氧疗 三乙醇胺 芦荟 

分 类 号：R730.55[医药卫生—肿瘤]