SERK Receptor-like Kinases Control Division Patterns of Vascular Precursors and Ground Tissue Stem Cells during Embryo Development in Arabidopsis  

作　　者：Huiqiang Li Zeping Cai Xiaojuan Wang Meizhen Li Yanwei Cui Nan Cui Fei Yang Mingsong Zhu Junxiang Zhao Wenbin Du Kai He Jing Yi Frans E.Tax Suiwen Hou Jia Li Xiaoping Gou 

机构地区：[1]Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, China [2]College of Forestry, Hainan University, Danzhou, Hainan 571737, China [3]Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA

出　　处：《Molecular Plant》2019年第7期984-1002,共19页分子植物（英文版）

基　　金：National Natural Science Foundation of China (31770312, 31530005, 31471402, 31720103902, 31270229, 31070283);the Ministry of Education (113058A. NCET-12-0249);the 111 Project (B16022);the Fundamental Research Funds for the Central Universities (lzujbky-2018-kb05);the Gansu Provincial Science & Technology Department (17ZD2NA015-06, 17ZD2NA016-5).

摘　　要：During embryo development, the vascular precursors and ground tissue stem cells divide to renew them-selves and produce the vascular tissue, endodermal cells, and cortical cells. However, the molecular mech-anisms regulating division of these stem cells have remained largely elusive. In this study, we show that loss of function of SOMATIC EMBRYOGENESIS RECEPTOR-UKE KINASE (SERK) genes results in aberrant em-bryo development. Fewer cortical, endodermal, and vascular cells are generated in the embryos of serk1 serk2bak1 triple mutants. WUSCHEL-RELATED HOMBOBOX5 (WOXS) is ectopically expressed in vascular cells of serkl serk2 bak1 embryos. The first transverse division of vascular precursors in mid-globular em-bryos and second asymmetric division of ground tissue stem cells in early-heart embryos are abnormally altered to a longitudinal division. The embryo defects can be partially rescued by constitutively activated mitogen-activated protein kinase (MAPK) kinase kinase YODA (YDA) and MAPK kinase MKK5. Taken together, our results reveal that SERK-mediated signals regulate division patterns of vascular precursors and ground tissue stem cells, likely via the YDA-MKK4/5 cascade, during embryo development.

关 键 词：EMBRYO GROUND TISSUE stem cell MKK4 MKK5 SERKs VASCULAR precursors 

分 类 号：Q[生物学]