老年脑卒中后抑郁症及神经功能康复的临床治疗研究  

Clinical Treatment of Post-stroke Depression and Neurological Rehabilitation in the Elderly

作　　者：邱静 QIU Jing(Department of Internal Medicine,Integrated Traditional Chinese and Western Medicine,the People's Hospital of Beiliu City,Yulin,Guangxi,537400 China)

机构地区：[1]北流市人民医院中西医结合内科

出　　处：《中外医疗》2019年第22期67-69,共3页China & Foreign Medical Treatment

摘　　要：目的针对老年脑卒中后抑郁症及神经功能康复的临床治疗进行研究。方法方便选取该院2016年12月—2018年11月收治的180例老年脑卒中后抑郁症患者,并按照随机数字表法分为对照组和观察组,各90例,两组患者均实施常规对症治疗(药物及康复疗法等),在此基础上给予对照组老年患者给予奥拉西坦药物治疗,观察组老年患者给予氟哌噻吨美利曲辛片药物治疗,观察两组老年患者的抑郁症改善情况(SDS评分)、神经功能康复情况(NIHSS评分)和Barthel指数。结果治疗前,两组患者SDS评分、NIHSS评分和Barthel指数比较差异无统计学意义(P>0.05);治疗后,两组患者SDS评分和NIHSS评分均低于治疗前,Barthel指数均高于治疗前,且观察组SDS评分(42.10±4.00)分和NIHSS评分(3.25±1.25)分低于对照组(P<0.05),Barthel指数(72.60±15.95)分高于对照组,差异有统计学意义(t=21.899,20.213,10.195,P<0.05)。结论老年脑卒中后抑郁症患者采取氟哌噻吨美利曲辛片治疗,抑郁症及神经功能康复情况均有所改善,且日常生活能力有所提高,具有临床应用价值。Objective To study the clinical treatment of post-stroke depression and neurological rehabilitation in the elderly.Methods Convenient a total of 180 elderly patients with post-stroke depression admitted to our hospital from December 2016 to November 2018 were enrolled.The patients were divided into the control group and the observation group according to the random number table,90 cases in each group,symptomatic treatment(drugs and rehabilitation therapy,etc.),on the basis of this,the elderly patients in the control group were given oxiracetam drug treatment,and the elderly patients in the observation group were given flupentixol melitracerol tablets for treatment,depression improvement(SDS score),neurological rehabilitation(NIHSS score),and Barthel index.Results Before treatment,there was no significant difference in SDS score,NIHSS score and Barthel index between the two groups(P>0.05).After treatment,the SDS score and NIHSS score of the two groups were lower than before treatment,and the Barthel index was higher than that before treatment.Before treatment,the SDS scores(42.10±4.00)points and NIHSS scores(3.25±1.25)points were lower in the observation group than in the control group(P<0.05),and the Barthel index(72.60±15.95)points was higher than the control group,the difference was statistically significant(t=21.899,20.213,10.195,P<0.05).Conclusion Elderly patients with post-stroke depression treated with flupentixol melitracex tablets have improved depression and neurological rehabilitation,and have improved daily living ability,which has clinical application value.

关 键 词：老年脑卒中 抑郁症 神经功能康复 BARTHEL指数 

分 类 号：R743[医药卫生—神经病学与精神病学]