泮托拉唑治疗胃溃疡临床疗效观察  

Clinical Observation of Pantoprazole in the Treatment of Gastric Ulcer

作　　者：夏秀梅[1] XIA Xiumei(Department of Gastroenterology, Xiaogan Central Hospital,Xiaogan Hubei 432000, China)

机构地区：[1]孝感市中心医院消化内科

出　　处：《中国继续医学教育》2019年第25期156-158,共3页China Continuing Medical Education

摘　　要：目的探究观察泮托拉唑治疗胃溃疡临床疗效。方法2018 年1月—2019 年1 月间从笔者所在医院收治的胃溃疡患者中选取76 例,随机分为两组各38 例,对照组采取阿莫西林联合克林霉素治疗,观察组在此基础上加服泮托拉唑肠溶胶囊治疗,对比两组患者临床疗效,并记录比较胃溃疡复发率、幽门螺杆菌根除率。结果观察组疗效优于对照组(94.74% vs . 76.32%),胃溃疡复发率低于对照组(7.89% vs .36.84%),幽门螺杆菌根除率高于对照组(86.84% vs . 55.26%),差异具有统计学意义(P < 0.05)。结论泮托拉唑辅助治疗胃溃疡效果显著,可有效改善患者临床症状及预后,提高溃疡愈合率,加快炎症的消退,可在合理范围内推广应用。Objective To explore and observe the clinical efficacy of pantoprazole in the treatment of gastric ulcer. Methods 76 patients with gastric ulcer admitted to our hospital from January 2018 to January 2019 were randomly divided into two groups, 38 cases in each group. The control group was treated with tinidazole tablets combined with clindamycin, and the observation group was treated with pantoprazole sodium on the basis of this. The clinical efficacy of the two groups was compared, and the recurrence rate of gastric ulcer and the eradication rate of Helicobacter pylori were recorded and compared. Results The curative effect of the observation group was better than that of the control group (94.74% vs.76.32%). The recurrence rate of gastric ulcer was lower than that of the control group (7.89% vs.36.84%). The eradication rate of Helicobacter pylori was higher than that of the control group (86.84% vs.55.26%). The difference was statistically significant (P<0.05). Conclusion Pantoprazole is an effective adjuvant therapy for gastric ulcer. It can effectively improve the clinical symptoms and prognosis of patients, improve the healing rate of ulcer, and accelerate the disappearance of inflammation. Pantoprazole can be widely used in a reasonable range.

关 键 词：泮托拉唑 胃 溃疡 临床 疗效 观察 

分 类 号：R573[医药卫生—消化系统]