脑血管介入栓塞疗法辅助立体定向放射治疗高血运性脑肿瘤的效果  

Effect of cerebrovascular interventional embolization therapy assisted with stereotactic radiotherapy therapy in the treatment of hypervascular brain tumors

作　　者：杜方雷 纪文军[1] 马小红[1] DU Fang-lei;JI Wen-jun;MA Xiao-hong(Neurosurgery Department, Yulin No.2 Hospital, Yulin 719000, China)

机构地区：[1]榆林市第二医院神经外科

出　　处：《临床医学研究与实践》2019年第24期56-58,共3页Clinical Research and Practice

摘　　要：目的探讨脑血管介入栓塞疗法辅助立体定向放射(SRT)治疗高血运性脑肿瘤的效果。方法选择我院2015年3月至2017年3月收治的82例高血运性脑肿瘤患者为研究对象,根据治疗方法的不同将其分为对照组与研究组,各41例。对照组给予SRT治疗,研究组给予SRT辅助脑血管介入栓塞疗法进行治疗。比较两组临床疗效、治疗前、后神经功能和生活质量评分、毒副反应发生情况及生存期。结果研究组患者的客观缓解率为78.05%,对照组患者的客观缓解率为51.22%,研究组的客观缓解率显著高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者的神经功能和生活质量评分比较,差异不具有统计学意义(P>0.05);治疗后,两组患者的神经功能评分均降低,生活质量评分均升高,且研究组均优于对照组,差异均具有统计学意义(P<0.05)。两组患者毒副反应发生情况比较,差异无统计学意义(P>0.05)。研究组患者的无进展生存期及总生存期均长于对照组,差异有统计学意义(P<0.05)。结论脑血管介入栓塞疗法辅助SRT治疗高血运性脑肿瘤的效果显著,可有效改善患者的神经功能和预后,改善患者的生活质量,且未增加不良反应,值得临床推广应用。Objective To explore the effect of cerebrovascular interventional embolization therapy assisted with stereotactic radiotherapy therapy (SRT) in the treatment of hypervascular brain tumors. Methods Eighty-two patients with hypervascular brain tumors admitted in our hospital from March 2015 to March 2017 were selected as the study objects and divided into control group and study group according to different treatment methods, with 41 cases in each group. The control group was treated with SRT, while the study group was treated with cerebrovascular interventional embolization therapy assisted with SRT. The clinical efficacy, the scores of neurological function and quality of life before and after treatment, occurrence of toxic and side effects and survival time were compared between the two groups. Results The objective remission rate was 78.05% in the study group and 51.22% in the control group;the objective remission rate in the study group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05). Before treatment, there were no significant differences in the scores of neurological function and quality of life between the two groups (P>0.05);after treatment, the scores of neurological function in both groups decreased, and the scores of quality of life in both groups increased, and those in the study group were better than the control group, and the differences were statistically significant (P<0.05). There was no significant difference in the occurrence of toxic and side effects between the two groups (P>0.05). The progression-free survival and total survival of the study group were longer than those of the control group, and the differences were statistically significant (P <0.05). Conclusion Cerebrovascular interventional embolization therapy assisted with SRT in the treatment of hypervascular brain tumors has a significant effect, which can effectively improve the neurological function, prognosis and the quality of life of patients, without increasing a

关 键 词：脑血管介入栓塞疗法 立体定向放射法 高血运性脑肿瘤 

分 类 号：R739[医药卫生—肿瘤]